Showing titles in History & Commentary

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.

With a death toll of between 50 and 100 million people and a global reach, the Spanish flu of 1918–1920 was the greatest human disaster. And yet, in our popular conception it exists largely as a footnote to World War I. Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered, and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.

The Quaker City and its hospitals were pioneers in the field of mental health. Yet by the end of the nineteenth century, its institutions were crowded and patients lived in shocking conditions. The mentally ill were quartered with the dangerously criminal. By 1906, the city had purchased a vast acreage of farmland incorporated into the city, and the Philadelphia Hospital dubbed its new venture Byberry City Farms. From the start, its history was riddled with corruption and committees, investigations and inquests, appropriations and abuse.

For over 40 years Barbara Seaman has been a leading women’s health advocate. Now she blows the lid off the estrogen industry in this fascinating book that holds the power to improve—possibly even save—women’s lives. In America 30 million women take estrogen. Seaman shows that this powerful hormone is hardly the cure-all some claim it is. In fact, estrogen treatments may increase the risk of cancer, heart disease, and osteoporosis.

One hundred years after a milestone medical discovery, Insulin: The Crooked Timber tells the story of how insulin was transformed from what one clinician called "thick brown muck" into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Taking the listener on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, the book reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes.

Singular Intimacies is the story of becoming a doctor by immersion at Bellevue Hospital, the oldest public hospital in the country—and perhaps the most legendary. It is both the classic inner-city hospital and a unique amalgam of history, insanity, beauty, and intellect. When Danielle Ofri enters these 250-year-old doors as a tentative medical student, she is immediately plunged into the teeming world of urban medicine: mysterious illnesses, life-and-death decisions, patients speaking any one of a dozen languages, and overworked interns.

The COVID-19 pandemic is the most significant health emergency of our time. Writing from Italy in lockdown, physicist and novelist Paolo Giordano explains how disease spreads in our interconnected world.

A missed clue. A wrong diagnosis. Sometimes the greatest danger comes not from illness itself, but from human error. In Medical Mysteries – Misdiagnosed, bestselling author Dean Lawton explores 20 real-life cases where patients suffered, struggled, and sometimes triumphed despite catastrophic medical mistakes. From wrong-leg amputations to deadly missed infections, these gripping true stories reveal the razor-thin margin between life and death when critical details are overlooked. How did a man survive months of unnecessary cancer treatments he never needed? What caused a young boy’s "...

Outlining how generations of public health and science advocates have attempted to hold the line against Big Pharma and their allies in government, Alexander Zaitchik's first-in-kind history documents the rise of medical monopoly in the United States and its subsequent globalization. From the controversial arrival of patent-wielding German drug firms in the late 19th century, to present-day coordination between industry and philanthropic organizations, Owning the Sun tells one of the most important and least understood histories of our time.

It’s a Darien, Connecticut, tradition: an emergency medical service managed by adolescents. One kid is a varsity soccer captain. There’s a future doctor, a band dork, a theater geek. Theirs is a view of town without the niceties. A drunken spouse turned violent. Lonely old people stuck in the bath. A midlife suicide. How do these kids process the sometimes shocking and violent life-and-death secrets of their community? The answer is a story of high stress and uncommon high school lives, told by a writer who spent his own youth on the night shift. Welcome to Post 53.

“Not all enemies wear faces. Not all heroes seek fame.” It came without a warning. No horns. No fire. No crashing skies. Just breath… carrying more than air. An invisible presence moved through us—quietly, quickly, and without favour. It didn’t ask for passports. It didn’t care about class. It didn’t knock before entering. And suddenly… everything we thought we knew about safety, community, and survival unravelled. We panicked. We scrambled. We blamed. But slowly… Quietly… We remembered. That cleanliness is not just a habit. It is a shield.

Weaving together family history, genetic discovery, and scenes from her life, Ami McKay tells the compelling, true-science story of her own family's unsettling legacy of hereditary cancer while exploring the challenges that come from carrying the mutation that not only killed many people you loved, but might also kill you.

For 4,000 years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since common response to the threat was exclusion — quarantining the sick or keeping them out. But the unprecedented hygiene and medical revolutions of the past two centuries have allowed humanity to free itself from the hold of epidemic cycles — resulting in an urbanized, globalized, and unimaginably wealthy world.

Maneater is a personal account by a specialist who approaches her work like a forensic scientist or a case-hardened private eye. Dr. Pamela Nagami is a leading authority on infectious diseases and her stories will shock, amaze, and warn listeners.The patients in Maneater are ordinary Americans. When Danielle Jordan innocently ordered a salad for lunch in Puerta Vallarta she had no idea she had just become the "host" to an organism that six years later would grow into a worm and burrow into her brain.

In The Invention of the Modern Dog, Michael Worboys, Julie-Marie Strange, and Neil Pemberton explore when, where, why, and how Victorians invented the modern way of ordering and breeding dogs. Though talk of "breed" was common before this period in the context of livestock, the modern idea of a dog breed defined in terms of shape, size, coat, and color arose during the Victorian period in response to a burgeoning competitive dog show culture.

The second-century Greek physician Galen—the most famous doctor in antiquity after Hippocrates—is a central figure in Western medicine. A talented doctor, surgeon, writer, philosopher, teacher, pharmacologist, and inventor, Galen attended the court of Marcus Aurelius, living through outbreaks of plague that devastated the Roman Empire. He also served as a physician for professional gladiators. In writings that provided the foundation of Western medicine up to the nineteenth century, Galen created a unified account of health and disease.

In this scientific detective story and a case study in the social construction of mass psychogenic illness, the authors provide dozens of examples of kindred episodes of mass hysteria throughout history, in addition to psychosomatic conditions and even the role of insects in triggering outbreaks.

In Good Blood, best-selling writer Julian Guthrie tells the gripping tale of the race to cure a horrible affliction known as Rh disease that stalked families and caused a mother’s immune system to attack her own unborn child. The story is anchored by two very different men on two continents: Dr. John Gorman in New York, who would land on a brilliant yet contrarian idea, and the unassuming Australian whose almost magical blood - and his unyielding devotion to donating it - would save millions of lives.

From Canada’s top war historian, a definitive medical history of the Great War, illuminating how the carnage of modern battle gave birth to revolutionary life-saving innovations. It brings to light shocking revelations of the ways the brutality of combat and the necessity of agonizing battlefield decisions led to unimaginable strain for men and women of medicine who fought to save the lives of soldiers.

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