This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

In the winter of 1918, at the height of World War I, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 weeks than AIDS has killed in 24 years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision between modern science and epidemic disease.

Breathless is story of SARs-CoV-2 and its fierce journey through the human population, as seen by the scientists who study its origin, its ever-changing nature, and its capacity to kill us. David Quammen expertly shows how strange new viruses emerge from animals into humans as we disrupt wild ecosystems and how those viruses adapt to their human hosts, sometimes causing global catastrophe. He explains why this coronavirus will probably be a “forever virus,” destined to circulate among humans and bedevil us endlessly, in one variant form or another.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

Respected physician Paul Offit tells a fascinating story of modern medicine and pays tribute to one of the greatest lifesaving breakthroughs—vaccinations—and the medical hero responsible for developing nine of the big fourteen vaccines which have saved billions of lives worldwide.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

Thomas Jefferson asserted that if there was any leader of the Revolution, “Samuel Adams was the man.” With high-minded ideals and bare-knuckle tactics, Adams led what could be called the greatest campaign of civil resistance in American history. Stacy Schiff returns Adams to his seat of glory, introducing us to the shrewd and eloquent man who supplied the moral backbone of the American Revolution, bringing her masterful skills to Adams’s improbable life, illuminating his transformation from aimless son of a well-off family to tireless, beguiling radical who mobilized the colonies.

In 1965, the US government helped the Indonesian military kill approximately one million innocent civilians. This was one of the most important turning points of the 20th century, eliminating the largest communist party outside China and the Soviet Union and inspiring copycat terror programs in faraway countries like Brazil and Chile. But these events remain widely overlooked, precisely because the CIA's secret interventions were so successful.

Although hints of a crisis appeared as early as the 1570s, the temperature by the end of the 16th century plummeted so drastically that Mediterranean harbors were covered with ice, birds literally dropped out of the sky, and "frost fairs" were erected on a frozen Thames - with kiosks, taverns, and even brothels that become a semi-permanent part of the city. Recounting the deep legacy and far-ranging consequences of this "Little Ice Age", acclaimed historian Philipp Blom reveals how the European landscape had subtly, but ineradicably, changed by the mid-17th century.

By the end of 19th century, food manufacturers had rushed to embrace the rise of industrial chemistry and were knowingly selling harmful products. Unchecked by government regulation, basic safety, or even labelling requirements, they put profit before health. Then, In 1883, Dr. Harvey Washington Wiley, a chemistry professor from Purdue University, was named chief chemist of the agriculture department, and the agency began methodically investigating food and drink fraud, even conducting shocking human tests on groups of young men who came to be known as, "The Poison Squad".

In September 2016, a woman in Nevada became the first known case in the US of a person who died of an infection resistant to every antibiotic available. Her death is the worst nightmare of infectious disease doctors and public health professionals. While bacteria live within us and are essential for our health, some strains can kill us. As bacteria continue to mutate, becoming increasingly resistant to known antibiotics, we are likely to face a public health crisis of unimaginable proportions.

At least one-third of the people we know are introverts. They are the ones who prefer listening to speaking; who innovate and create but dislike self-promotion; who favor working on their own over working in teams. It is to introverts—Rosa Parks, Chopin, Dr. Seuss, Steve Wozniak—that we owe many of the great contributions to society.

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

A major new biography of J Edgar Hoover that draws from never-before-seen sources to create a groundbreaking portrait of a colossus who dominated half a century of American history and planted the seeds for much of today's conservative political landscape.