The death of a nameless young woman in his emergency room spurs physician AJ Docker to seek answers. Together with his policeman friend and a police dog, he sets out on a quest for justice for his lost patient, but he discovers more questions than answers as he delves into the criminal world.

Suspicious deaths. Broken bonds. Lives in peril. Redemption. Past-haunted emergency physician Zack Winston and case-hardened defense attorney Bridget Larsen battle a malicious malpractice suit. They uncover a medical conspiracy trading in drugs and murder. As they peel back layers of truth, past relationships and current alliances destabilize-threatening both their lives. A new bond ignites between them.

Dr. Jacey Flanigan has worked tirelessly to achieve her dream of becoming a pediatric cardiologist. But when she moves to Manhattan to begin her career at a prestigious children's hospital, she discovers that the medical profession may not be what she expected. An encounter with an arrogant heart surgeon on her first day sets the tone for what's to come - a world of enigmatic physician behavior and questionable cardiac surgical practices cloaked in secrecy.

Across the Pacific Northwest, a twisted killer stalks victims representing ancient archetypes: The Ruler. The Warrior. The Scholar. The Priest. Four are dead, leaving FBI investigators puzzled by the macabre, color-coded shrines the killer left behind. And clues now point to a fifth victim.

Thomas Austin was once a prominent NYPD detective, known for locking up a psychopathic serial killer dubbed "The Holiday Baby Butcher". Now retired in a small beach town in the Pacific Northwest, Austin runs a little café, trying to overcome the loss of his wife, a DA who was gunned down only one year ago.

Failed surgeon David McBride is in exile from the surgical community after making a costly error in judgment. Down but not out, he perseveres and is given a second chance to establish a career in surgery. But, as McBride stands on the threshold of a new life, the malignant underside of his fellow man intervenes. Under the threat of violence, David is forced to perform illegal organ harvests in a makeshift operating room hidden in a dilapidated meatpacking warehouse in lower Manhattan.

Showrunner Ethan Harris had a hit with The Murder Show, a television crime drama that features a private detective who solves cases the police can’t. But after his pitch for the fourth season is rejected by the network, he returns home to Minnesota looking for inspiration. His timing is fortunate—his former classmate Ro Greeman is now a local police officer, and she's uncovered new information about the devastating hit and run that killed their mutual friend Ricky the summer after high school. She asks Ethan to help her investigate.

Accidents happen, no matter how careful or well-intentioned you are. Psychiatrist Eve Thayer frequently reassures her patients of that fact. There are even times when accidents have good consequences—like when Eve met her now-husband, Nathan, at his collision shop after another car ran her off the road. After a whirlwind courtship, Nathan and Eve have settled into domestic life. They have a lovely home on a quiet street, a beautiful baby girl, and even the perfect babysitter to care for her. And yet, something isn’t quite right.

Police Chief Jeep Mullane has been bounced back home to Long Island’s North Shore by a heartbreaking case that both earned him his NYPD detective’s shield and burned him out of the Job. Now heading up a small local police department, he finds himself navigating the same geography he did growing up there as the son of an NYPD cop. Jeep is a “have-not” among the glittering “haves,” a sharp-witted, down-to-earth man in a territory defined and ruled by multigenerational wealth and power and the daunting tribal codes and customs that come with it.

For San Francisco’s newest medical examiner, Dr. Jessie Teska, it was supposed to be a fresh start. A new job in a new city. A way to escape her own dark past. Instead, she faces a chilling discovery when an opioid-overdose case contains hints of something more sinister. Jessie’s superiors urge her to close the case, but as more bodies land on her autopsy table, she uncovers a constellation of deaths that point to an elaborate plot involving drug dealers and Bitcoin brokers.

Attorney Nate Shepherd left a big firm to go out on his own. He sees nothing but opportunity when an out-of-town lawyer wants to hire him as local counsel on a high-profile murder case. Though his family worries that the case hits too close to home, Nate joins the defense team. When circumstances force him to take on a bigger role, Nate ignores his family’s fears and throws himself into his client’s defense.

Twenty-eight-year-old Sean McGillin is the picture of health, until he fractures his leg while in-line skating in New York City's Central Park. Within 24 hours of his surgery, he dies.

After the tragic loss of their young son to a rare genetic disorder, John and Naomi discover they both carry a rogue gene. Having another child by conventional means is too much risk to bear. When they find geneticist Dr. Leo Dettore, it seems like the answer to their prayers. Every aspect of the child can be chosen and manufactured, from height and eye color to intelligence and sporting prowess. But realizing the danger too late, Naomi is already pregnant when they understand the nightmare world they are entering.

Dr. Jack Wyatt is renowned for solving the unsolvable. When a colleague approaches him about a dangerous new malady affecting only Leukemia patients at a prestigious oncology hospital, the mysterious case is too intriguing to pass up. So he and the brilliant Dr. Madison Shaw, a physician who shares not only his expertise but also his devotion to medicine, embark in a race against time to save the children as cases mount. Within the hospital walls, they confront a labyrinth of medical conundrums, hostile colleagues guarding their territory, and a web of political intrigue.

Dr. Duncan Lathram is a brilliant plastic surgeon who recently invented a dissolving implant that allows incisions to heal without scarring. His unparalleled artistry in the operating room is the salvation of all the biggest power players in Washington, DC, whenever they need to be TV ready. Lathram appears to have it all, but something isn’t right....