At 32 Russell Green has it all: a stunning wife, a lovable six-year-old daughter, a successful career as an advertising executive, and an expansive home in Charlotte. He is living the dream, and his marriage to the bewitching Vivian is the center of that. But underneath the shiny surface of this perfect existence, fault lines are beginning to appear, and no one is more surprised than Russ when he finds every aspect of the life he took for granted turned upside down.

Christopher and Hannah are a happily married surgeon and nurse with picture-perfect lives. All that’s missing is a child. When Janie, an abandoned six-year-old, turns up at their hospital, Christopher forms an instant connection with her, and he convinces Hannah they should take her home as their own.

For 12-year-old Cora Landry and her friends Violet and Jordyn, it was supposed to be an ordinary sleepover - movies and Ouija and talking about boys. But when they decide to sneak out to go to the abandoned rail yard on the outskirts of town, little do they know that their innocent games will have dangerous consequences. Later that night, Cora Landry is discovered on the tracks, bloody and clinging to life, her friends nowhere to be found. Soon, their small rural town is thrust into a maelstrom. Who would want to hurt a young girl like Cora - and why?

Competitive skier Mindy Wright is a superstar in the making until a spectacular downhill crash threatens not just her racing career but her life. During surgery, doctors discover she’s suffering from a severe form of leukemia, and a stem cell transplant is her only hope. But when her parents are tested, a frightening truth emerges. Mindy is not their daughter.

Being the middle child has its ups and downs. But for Grace, an only child who was adopted at birth, discovering that she is a middle child is a different ride altogether. After putting her own baby up for adoption, she goes looking for her biological family, including: Maya, her loudmouthed younger bio sister, who has a lot to say about their newfound family ties. And Joaquin, their stoic older bio brother, who has no interest in bonding over their shared biological mother.

Abbie MacIntyre is living the dream in the picturesque Nova Scotia town she calls home. She is a successful surgeon, is married to a handsome cardiologist, and has a model teenage son who is only months away from going off to college. But then one fateful night, everything changes. When a drunk driver hits her car, Abbie is rushed to the hospital. She survives, but the accident forces unimaginable secrets out into the open and plagues Abbie with nightmares so vivid that she starts to question her grip on reality.

"I am a survivor of horrific physical and mental abuse inflicted on me by the one person in my life that was supposed to love and protect me and teach me right from wrong.... My journey to overcome my childhood demons was difficult and painful; but in the end, I realized that my past is what it is and it was up to me to decide my future. I realized that I needed to tell the rest of my story and show everyone what I endured to finally be able to sit back and say, 'It is what it is.'"

Melissa had clung to the thin thread of hope given by the adoption agency that someday her newborn son might want to connect with her. When his eighteenth birthday arrived, she called the agency to simply update her contact information, not expecting a response.

At the age of 29, Hannah Martin still has no idea what she wants to do with her life. She has lived in six different cities and held countless meaningless jobs since graduating college. On the heels of leaving yet another city, Hannah moves back to her hometown of Los Angeles and takes up residence in her best friend Gabby’s guestroom. Shortly after getting back to town, Hannah goes out to a bar one night with Gabby and meets up with her high school boyfriend, Ethan. Just after midnight, Gabby asks Hannah if she’s ready to go. A moment later, Ethan offers to give her a ride.

All their lives, Alice Stanhope and her daughter, Zoe, have been a family of two, living quietly in Northern California. Zoe has always struggled with crippling social anxiety, and her mother has been her constant and fierce protector. With no family to speak of and the identity of Zoe's father shrouded in mystery, their team of two works - until it doesn't. Until Alice gets sick and needs to fight for her life. Desperate to find stability for Zoe, Alice reaches out to two women who are practically strangers but who are her only hope: Kate, a nurse, and Sonja, a social worker.

It started with a bus crash. Daisy was a little girl when it happened, and she barely remembers the accident or being brought back to life. At that moment, though, she became one of the first subjects in a covert government program that tests a drug called Revive. Now fifteen, Daisy has died and been Revived five times. Each death means a new name, a new city, and a new identity. The only constant in Daisy’s life is change. Then she meets Matt and Audrey, charismatic siblings who quickly become her first real friends....

Dear Anna, What I have to tell you is difficult to write, but I know it will be far more difficult for you to hear, and I'm so sorry. The unfinished letter is the only clue Tara and Emerson have to the reason behind their close friend Noelle's suicide. Everything they knew about Noelle - her calling as a midwife, her passion for causes, her love for her friends and family - described a woman who embraced life. Yet there was so much they didn't know. With the discovery of the letter and its heartbreaking secret, Noelle's friends begin to uncover the truth about this complex woman who touched each of their lives.

Thirty-six-year-old Grace McAllister never longed for children. But when she meets Victor Hansen, a handsome, charismatic divorced restaurateur who is father to Max and Ava, Grace decides that, for the right man, she could learn to be an excellent part-time stepmom. After all, the kids live with their mother, Kelli. How hard could it be?

Stay-at-home mom Piper Whitman Hart is too close to her nine-year-old son, Fred, to realize that his idiosyncrasies are signs of something more. And just when his diagnosis of autism sends her life reeling, she's dragged back into the orbit of her emotionally abusive father, Lance, after a heart attack leaves him with brain damage.

Emily, a popular but bookish prep school senior, goes missing after a night out with friends. She was last seen leaving a party with Alex, a football player with a dubious reputation. But no one is talking. Now three mothers, Catherine, Leslie and Morgan, friends turned frenemies, have their lives turned upside down as they are forced to look to their own children—and each other’s—for answers to questions they don’t want to ask.