How powerful is exercise in the fight against advanced prostate cancer? Dr. Geo speaks with world-renowned exercise oncology expert Dr. Rob Newton from Australia, whose groundbreaking research has shaped how clinicians approach fitness and cancer care. From bone metastasis to androgen deprivation therapy (ADT), Dr. Newton explains how the right exercise, at the right dose, can not only improve quality of life but potentially extend it.

Together, they explore the science, practical guidelines, and inspiring stories behind using movement as medicine—even for men with metastatic, castration-resistant disease.

Key Takeaways

• Exercise is medicine for men with prostate cancer—including advanced and metastatic cases.
• Resistance training helps preserve or build muscle during androgen deprivation therapy (ADT), reducing side effects like fatigue, bone loss, and metabolic issues.
• Even with bone metastases, exercise can be done safely with modified strength programs—no increase in fractures observed in studies.
• Muscle strength and fitness are strongly linked to lower cancer-related and all-cause mortality.
• Myokines released from working muscles have direct anti-cancer effects and support immune function.
• Focus on large muscle groups (legs, back, chest) using moderate to heavy weights—6 to 15 reps per set.
• Tailor workouts to the individual: more strength training for muscle loss, more cardio for heart/metabolic risk.
• Periodized, varied routines improve outcomes and help patients tolerate treatments like chemo better.

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