A debate on the mind, soul, consciousness, and the afterlife.

Michael Egnor, MD, is Professor of Neurosurgery and Pediatrics at the Renaissance School of Medicine at Stony Brook University. He received his medical degree from the College of Physicians and Surgeons at Columbia University and trained in neurosurgery at the University of Miami. He has been on faculty at Stony Brook since 1991. He is the neurosurgery residency director and has served as the director of pediatric neurosurgery and as vice-chairman of neurosurgery at Stony Brook Medicine. He has a strong interest in Thomistic philosophy, philosophy of mind, neuroscience, evolution and intelligent design, and bioethics and has published and lectured extensively on these topics. His new book is The Immortal Mind: A Neurosurgeon’s Case for the Existence of the Soul.

Christof Koch is a neuroscientist at the Allen Institute and at the Tiny Blue Dot Foundation, the former president of the Allen Institute for Brain Science, and a former professor at the California Institute of Technology. Author of four previous titles—The Feeling of Life Itself: Why Consciousness Is Widespread but Can’t Be Computed, Consciousness: Confessions of a Romantic Reductionist, and The Quest for Consciousness: A Neurobiological Approach—Koch writes regularly for a range of media, including Scientific American. His latest book is Then I Am Myself the World.

When award-winning science writer Amy Alkon was blindsided by her first hot flash, it kicked off a cascade of symptoms—drenching night sweats, insomnia, and a rage she couldn’t explain. But what shocked her more was how little real science her doctor had to offer.

In this episode, Alkon shares what she uncovered in her deep dive into the research on menopause and perimenopause—the critical yet often neglected years leading up to menopause when millions of women are misdiagnosed, dismissed, or simply told to “wait it out.” Drawing from her new book Going Menopostal, she explains why so much medical advice is still based on outdated or inadequate evidence, and what women can do about it.

Alkon breaks down complex science with clarity, humor, and a healthy dose of skepticism, giving listeners the tools they need to ask better questions, advocate for themselves, and get the care they deserve. Whether you’re in the thick of it or simply want to be prepared, or want to support your loved ones going through menopause, this episode will leave you informed, empowered, and maybe even laughing.

Amy Alkon is an independent investigative science writer specializing in “applied science”—using scientific evidence to solve real-world problems. Alkon critically evaluates and synthesizes research across disciplines and then translates it into everyday language, empowering regular people to make scientifically informed decisions for the best of their health and well-being.

For 25 years, Alkon wrote an award-winning, science-based nationally syndicated advice column, distributed by Creators. She is the author of five books—most recently, her “science-help” book Unf*ckology: How to Live with Guts and Confidence (St. Martin’s Press, 2018). She is the past President of the Applied Evolutionary Psychology Society, which brings evolutionary science to public policy, education, and medicine. Her new book is Going Menopostal: What You (And Your Doctor) Need to Know About the Real Science of Menopause and Perimenopause.

What began as a call for justice has, in many cases, become an engine of conformity. In this searching conversation, Andrew Doyle (author, satirist, and cultural critic) joins Michael Shermer to unpack the trajectory of the woke movement: from its roots in anti-bigotry and awareness to its current entanglement with censorship, identitarian dogma, and ideological rigidity.

Drawing on his new book, The End of Woke Doyle traces the intellectual history of contemporary activism, explores the authoritarian impulses emerging on both the left and the right, and makes the case for a return to classical liberalism as a defense against escalating cultural tribalism.

Together, Shermer and Doyle explore themes ranging from the legacy of Shakespeare and Milton, the tension between equality and meritocracy, and the broader sociopolitical dynamics shaping public discourse.

This episode offers a sharp, historically grounded analysis of one of the defining cultural shifts of our time—and a call to revive liberal principles in the face of rising ideological orthodoxy.

Andrew Doyle is a writer, satirist and political commentator. He was formerly a Visiting Research Fellow at Queen’s University Belfast, and a lecturer at Oxford University where he completed his doctorate in Renaissance Literature. He is the creator of satirical character Titania McGrath, under whose name he has written two books: Woke: A Guide to Social Justice and My First Little Book of Intersectional Activism, both published by Little, Brown. Titania McGrath has over half a million followers on X. His previous books include Free Speech and Why it Matters and The New Puritans: How the Religion of Social Justice Captured the Western World. His new book is The End of Woke: How the Culture War Went Too Far and What to Expect from the Counter-Revolution.