Skin and Joints Podcast

By: Mimi Tran Aaron Sihota Danny Mansour Ashley Yip Julia Tan Touraj Khosravi Anastasiya Muntyanu
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  • Summary

  • A national multidisciplinary masterclass exploring inflammatory skin and joint related conditions led by healthcare experts from across Canada and the US.
    2024 Skin and Joints Podcast
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Biological Sciences Hygiene & Healthy Living Physical Illness & Disease Science
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Episodes
  • AAD Late Breaking Results from FLEX-UP with Dr. Melinda Gooderham and Dr. Angela Law

    AAD Late Breaking Results from FLEX-UP with Dr. Melinda Gooderham and Dr. Angela Law
    Apr 7 2025
    Episode: Do I start at 15 or jump straight to 30? Key Questions Answered: What’s the translational takeaway for dermatologists?🩺Do these findings reassure you about dose escalation or reduction?🤔15 mg vs. 30 mg-clinic conundrum solved🏷️🌴☀️ Sunshine, palm trees, and late-breaking dermatology data!🎙️💡 In this special live episode of the Skin and Joints Podcast, from the AAD 2025 in sunny Orlando, Florida, we breakdown the FLEX UP late breaking trial results for upadacitinib for moderate to severe atopic dermatitis with with two leading Canadian dermatologists: Dr. Melinda Gooderham and Dr. Angela Law!They also share their ultimate “conference flexes” We go beyond EASI, spotlighting itch control 🤲, quality of life, and real-world relevance 🏥 for all those asking, “So what does this mean practically?Together, our experts explore how this flexible dosing study answers a longstanding question: Should you start patients on the 15 mg or 30 mg dose, and can you switch between them for better results?Hear how this late-breaking data might recalibrate your go-to prescribing assessment and whether it’s time to tweak your approach.The discussion pokes at the trial’s design, why Week 12 and 24 were selected, the importance of itch reduction, and safety data. Dr. Gooderham and Dr. Law also weigh in on how these findings might—or might not—revolutionize current clinical practice. Learning ObjectivesFLEX UP Trial Design & RationaleGrasp how the study was structured to evaluate flexible dosing of upadacitinib at 15 mg and 30 mg.Clinical Efficacy MeasuresUnderstand the role of EASI 90, NRS, and quality-of-life metrics in gauging patient outcomes.Real-World ImplicationsExamine how FLEX UP data supports practical dosing choices—starting big or small—and equips you to address patient questions about switching doses.Safety & TolerabilitySummarize the key safety findings (including VTE, serious infections, and zoster) and how they align with existing JAK-inhibitor data.Future DirectionsRecognize the need for longer-term follow-up and additional analyses to further refine flexible dosing strategies and patient selection.🌞 Grab a comfy pair of sneakers 👟 and a protein bar 🍫 because we’re tackling front-line, day-to-day dilemmas in AD management—once and for all! Expect wit, warmth, and wisdom in this fast-paced chat, complete with palm trees, protein bars, and plenty of pro tips. ABOUT DR. MELINDA GOODERHAMDermatologist, Peterborough, ON Dr. Melinda Gooderham is a well-established dermatologist who serves as medical director at the SKiN Centre for Dermatology and the principal investigator for the SKiN Research Centre. Dr. Gooderham received her MD from the University of Western Ontario in 1999 and then completed her Dermatology residency at the University of Toronto in 2004. Before training in medicine, Dr. Gooderham obtained a Bachelor of Science degree from Queen’s University in Kingston in 1992 and a Master of Science degree from the University of Guelph in 1995. Dr. Gooderham is an Assistant Professor at Queens University and works as a Consultant Physician at the Peterborough Regional Health Centre (PRHC). A fellow of the Royal College of Physicians and Surgeons of Canada, she has investigated over 200 clinical trials focusing on inflammatory skin diseases, including psoriasis and atopic dermatitis. Beyond clinical practice, Dr. Gooderham actively contributes to dermatology publications as an author, reviewer, and associate editor, with authorship of over 200 articles. Her passion for education extends to global audiences through engaging lectures on innovative therapies for skin diseases. About DR. ANGELA LAW MD, FRCPCDermatologist | VANCOUVER, BCDr. Angela Law is a board certified Dermatologist in both Canada and the United States. She completed her dermatology residency in a joint program at the University of Saskatchewan and Dalhousie University. She is a Clinical Instructor in the Department of Dermatology and Skin Science at UBC, regularly teaching medical students and residents, and runs the Urgent Dermatology Clinic at Mount Saint Joseph’s Hospital. She also has an active dermatology practice in downtown Vancouver.Dr. Law also runs the Vulvar Dermatology Clinic at Mount Saint Joseph’s Hospital which is an innovative clinic with a focus on Women’s Health within Providence Health Care.Episode supported by Abbvie.📻www.skinandjoints.ca✉️info@skinandjoints.ca 📻www.skinandjoints.ca✉️info@skinandjoints.ca
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    19 mins
  • Fall Clinical Cross Border Talk: A Breakthrough in Acne Sebum Reduction with Dr. Zoe Draelos & Dr. Andrei Metelitsa

    Fall Clinical Cross Border Talk: A Breakthrough in Acne Sebum Reduction with Dr. Zoe Draelos & Dr. Andrei Metelitsa
    Jan 20 2025
    Lights, laughter, and lasers on sebum?! 🤔 Absolutely!Join us for our first-ever Skin and Joints Podcast episode live at Fall Clinical 2024 in sunny Las Vegas. 🎰 We’re unveiling our new segment “Cross-Border Talk,” featuring Dr. Zoe Diana Dreyloos (reformed mechanical engineer ✈️ from North Carolina) and Dr. Andrei Medlitsa US-based dermatologist (hello, North Carolina!) and a Canadian colleague (brrr, Calgary!) trade professional pearls and unique perspectives on acne care.Expect runway-ready insights on:The big reveal of Clascoterone cream’s impact on sebum production (yep, they used a “sebum meter!”)Brand-new data showing significant improvements in both inflammatory and non-inflammatory acne lesionsThe “golden ticket” to fine dining in Vegas, plus confessions of flight fantasies (hint: not all high-flying action happens at the blackjack table)If you’re tired of your patients asking, “Doc, how do I zap this shine?”—this is the episode for you. Because (despite the famous saying) what happens in Vegas definitely won’t stay in Vegas this time. Tune in for the scoop on everything from sebum science to top-secret bunker restaurants. 🍸Episode Learning ObjectivesUnderstand the central role of sebum production in acne pathogenesis and how it shapes therapeutic strategies.Evaluate the newly released 12-week clinical data on Clascoterone cream 1%—with measured impact on both inflammatory and non-inflammatory lesions.Discuss the safety and tolerability profile of Clascoterone, including real-world patient adherence considerations.Translate the study’s findings into everyday practice, identifying which acne patients might benefit most from sebum-targeted therapy.Explore future research directions, including combination approaches, longer-term outcomes, and potential applications in severe acne or pore-size reduction.Understand the pivotal role of sebum production in acne pathogenesis and how it shapes therapeutic decisions.Examine the newest 12-week clinical data on Clascoterone cream 1%—including its documented impact on both inflammatory and non-inflammatory acne lesions.Apply practical tips for integrating Clascoterone into real-world regimens, tackling oily skin head-on with confidence.Get ready to rethink your acne game plan…Get ready for an antioxidant masterclass 🤓✨— that’ll have you completely rethinking your recommendations! ABOUT Dr. Zoe Diana Draelos, MD, FAADDERMATOLOGIST, HIGH POINT, NORTH CAROLINAZoe Diana Draelos, MD, is a research and clinical board-certified dermatologist and a Fellow of the American Academy of Dermatology. She is in solo private practice in High Point, North Carolina, and a Consulting Professor of Dermatology at Duke University. In 1988, she founded Dermatology Consulting Services, PLLC, to initiate and perform research in aging skin, acne, rosacea, psoriasis, atopic dermatitis, actinic keratoses, eczema, and aesthetic procedures in the cosmetic, OTC drug, and pharmaceutical arenas. Prior to pursuing a medical career, Dr. Draelos completed an undergraduate degree in Mechanical Engineering and was elected a Rhodes Scholar. A member of Sigma Xi research honorary and Alpha Omega Alpha medical honorary, she is author of 14 books including Cosmetics in Dermatology and Hair Cosmetics. She is the editor of Cosmetic Dermatology: Products and Procedures (third edition) and Cosmeceuticals (fourth edition) with translations into 7 languages. She has contributed chapters to 44 textbooks, written 173 posters, served as the principal investigator on 982 studies, written 650 published papers, served on or contributed to 38 journal editorial boards, functioned as the editor-in-chief of the Journal of Cosmetic Dermatology for 10 years, and was a past member of the Board of Directors of the American Academy of Dermatology and the American Society for Dermatologic Surgery. She was elected Vice-President of the American Academy of Dermatology. She is recognized as a pioneer in cosmetic dermatology and received a lifetime achievement award from Health Beauty America for her research and the 2008 DermArts award for her contributions to dermatology. In 2010, she received the Albert Kligman Innovation Award and in 2016 she was awarded a Presidential Citation from the American Academy of Dermatology for her research contributions to advance the specialty. She received the prestigious Maison deNavarre award from the Society of Cosmetic Chemists for her contributions to the art and science of cosmetics in 2017. In 2019, she was the inaugural recipient of the Florence Wall Award from the Society of Cosmetics Chemists naming her as the most influential women in cosmetic science.ABOUT Dr. Andrei Metelitsa, MD, FRCPC, FAADDERMATOLOGIST, CALGARY, ABDr. Metelitsa is a Board-Certified Dermatologist in both Canada and United States and is currently a Clinical Professor at the University of Calgary's Faculty of Medicine. He graduated from medical school...
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    29 mins
  • The Antioxidant RX: Protection Beyond SPF

    The Antioxidant RX: Protection Beyond SPF
    Dec 19 2024

    Hold onto your antioxidants—this episode of the podcast is a full-court press on free radicals!

    When it comes to the science of antioxidants and topical formulations, we have the right person-dermatologist Dr. Mark Lupin debuts as a faculty expert on the podcast to practically decipher what you NEED to know

    Also debuting on the podcast, but as a guest co-host, is dermatologist Dr. Vincent Richer who's ready to fire up the hot seat with pharmacist Aaron Sihota to ask the tough questions.

    Don’t miss our RAPID FIRE round where we break down must-know ingredients faster than you can say ‘free radical!’ 🚀🦸

    We dust off your old sunscreen routine and show you why slathering on antioxidants might just be your skin’s new secret weapon. Tune in for a fast-paced conversation that hops effortlessly from clinic chairs to concert halls, apples to ferulic acid, and vitamin C to conjugated retinol. Here, myths get busted, fancy science terms get decoded, and you’ll finally learn the ABCs of a top-tier skincare regimen—no sunscreen-shy patients or lost winter gloves required. ☀️🧴🍏

    Trust us, this episode is your on-demand playbook reference for practice! 🎧📖

    Learning Objectives:

    1. Antioxidant Fundamentals: Understand how environmental aggressors cause oxidative stress on the skin and how antioxidants serve as powerful defenders. The latest science on how these mighty molecules supercharge your broad-spectrum sunscreen and reduce UV-induced damage?🌞🔬 ‍🍃
    2. Key Ingredients in formulations: Identify evidence-based antioxidant ingredients, learn why they’re paired together, and explore optimal formulation concentrations and pH levels for maximum skin benefits. 🍏🔬
    3. Critical Evaluation of Research: Gain tools and strategies to discern credible studies from marketing fluff, ensuring more informed clinical recommendations. 📚🔎
    4. Integration into Practice: Discover practical tips for incorporating antioxidants into morning routines, combining them effectively with sunscreens, and managing patient expectations. ⏰✔️
    5. Future Directions in Dermatology: Explore the promising frontier of antioxidant research, including their potential to complement medical interventions and the call for standardized validation measures. 🔭🚀

    Get ready for an antioxidant masterclass 🤓✨— that’ll have you completely rethinking your recommendations!

    ABOUT DR.MARK LUPIN MD FRCPC DABD

    VICTORIA, BC

    Dr. Lupin is a Board-certified Dermatologist, Founder in 1998 of Cosmedica Laser Centre in Victoria, British Columbia and Chief Clinical Officer of MedSpa Partners Inc.He has degrees in Mathematics, Music and Medicine having studied at the University of Toronto, University of British Columbia, Dalhousie University, Indiana University and the University of Southern California. He has special interests in photodermatology and laser medicine, having studied under Professor John Hawk at St John’s Institute of Dermatology, London, England. He is active with research and education, has additional subspecialty training in Neurology and is past President of the Canadian Laser Aesthetic Surgery Society.

    As a concert violinist, Dr Lupin has performed as soloist at Carnegie Hall, New York and with major orchestras around the world. He is Concertmaster of the World Doctors Orchestra (WDO), performing most recently in Australia at the Sydney Opera House, with all proceeds donated to charities. His research interests extend to space medicine and fluid dynamics where he has been active with mathematical modeling for space tools and has developed several patent pending energy efficient devices.

    ABOUT Dr. Vincent Richer MD FRCPC

    VANCOUVER, BC

    Dr Vincent Richer practices cosmetic dermatology at Pacific Derm Atelier in Vancouver and holds a position as Clinical Assistant Professor at the University of British Columbia’s Department of Dermatology and Skin Science. He trained at Université de Montréal in Medicine and Dermatology and completed a fellowship in Photobiology and Cutaneous Laser Surgery at UBC. He is involved as a subinvestigator in cosmetic clinical trials, has published 35+ peer reviewed scientific articles and is active in undergraduate, graduate and continuing medical education.

    EPISODE SUPPORTED BY SKINCEUTICALS AND SKINBETTER SCIENCE.

    📻www.skinandjoints.ca

    ✉️info@skinandjoints.ca

    📻www.skinandjoints.ca

    ✉️info@skinandjoints.ca
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    31 mins
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