• Lactulose (Generlac)
    Aug 18 2023

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    Generic Name

    lactulose

    Trade Name

    Kristalose

    Indication

    Constipation, portal-systemic encephalopathy

    Action

    draws water into the stool and softens stool, inhibits ammonia passing into the colon

    Therapeutic Class

    laxative

    Pharmacologic Class

    osmotic

    Nursing Considerations

    • use caution with DM
    • may cause cramps, abdominal distention, hyperglycemia
    • assess mental status, ammonia levels, abdominal distention
    • patient should average 2-3 bowel movements per day

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    3 mins
  • Ketorolac (Toradol)
    Aug 16 2023

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    Generic Name

    ketorolac

    Trade Name

    Toradol

    Indication

    pain

    Action

    pain relief due to prostaglandin inhibition by blocking of the enzyme cyclooxygenase (COX)

    Therapeutic Class

    nonsteroidal anti-inflammatory agents, nonopioid analgesics

    Pharmacologic Class

    pyrroziline carboxylic acid

    Nursing Considerations

    • may cause GI bleeding, Stevens-Johnson Syndrome, anaphylaxis, drowsiness
    • should not exceed 5 days of therapy
    • bleeding risk increased with garlic, ginger, and ginkgo
    • may decrease effectiveness of hypertensive medications and diuretics

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    3 mins
  • Isoniazid (Niazid)
    Aug 14 2023

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    Generic Name

    isoniazide

    Trade Name

    INH

    Indication

    tuberculosis

    Action

    Inhibits synthesis of mycobacterial cell wall

    Therapeutic Class

    Antitubercular

    Pharmacologic Class

    none

    Nursing Considerations

    • can cause jaundice
    • may cause peripheral neuropathy, seizures, hepatitis
    • patient should avoid high amounts of tyramine (pickled meats, aged/smoked meats, alcohol, exotic/aged cheese)
    • monitor liver function tests
    • complete full course of therapy (6-12 months)
    • often used in combination with Rifampin

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    4 mins
  • Iodine
    Aug 11 2023

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    Generic Name

    radioactive iodine

    Trade Name

    none

    Indication

    thyroidectomy pretreatment, thyrotoxic crisis, radiation exposure

    Action

    inhibits the release of thyroid hormones

    Therapeutic Class

    Antithyroid Agent, control of hyperthyroidism

    Pharmacologic Class

    none

    Nursing Considerations

    • may cause GI bleeding, diarrhea, hypothyroidism, goiter
    • monitor for hypersensitivity

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    2 mins
  • Insulin – Short Acting (Regular)
    Aug 9 2023

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    Generic Name

    Insulin Regular

    Trade Name

    Humulin R/Novolin R

    Indication

    hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

    Action

    stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
    prevents breakdown of fat and protein

    RouteOnsetPeakDurationSubcutaneous30-45 min1-54.5-6h

    Therapeutic Class

    antidiabetics, hormones

    Pharmacologic Class

    pancreatics

    Nursing Considerations

    • assess for symptoms of hypoglycemia or hyperglycemia
    • monitor body weight over time
    • may cause decreased inorganic phosphates, potassium, and magnesium
    • monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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    4 mins
  • Insulin – Rapid Acting (Novolog, Humalog)
    Aug 7 2023

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    Generic Name

    Aspart, Lispro, Glulisine

    Trade Name

    Novolog, Humalog, Apidra

    Indication

    hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

    Action

    stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
    prevents breakdown of fat and protein

    Route OnsetPeakDurationAspart10-20 min1-3 hr3-5 hrGlulisine15 min1 hr2-4 hrLispro15 min1-1.5 hr3-4 hr

    Therapeutic Class

    antidiabetics, hormones

    Pharmacologic Class

    pancreatics

    Nursing Considerations

    • assess for symptoms of hypoglycemia or hyperglycemia
    • monitor body weight over time
    • may cause decreased inorganic phosphates, potassium, and magnesium
    • monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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    3 mins
  • Insulin – Long Acting (Lantus)
    Aug 4 2023

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    Generic Name

    Insulin detemir, Insulin glargine

    Trade Name

    Levemir, Lantus

    Indication

    hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

    Action

    stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
    prevents breakdown of fat and protein

    RouteOnsetPeakDurationDetemir3-4 hr3-14 hr24 hrGlargine3-4 hrnone24 hr

    Therapeutic Class

    antidiabetics, hormones

    Pharmacologic Class

    pancreatics

    Nursing Considerations

    • assess for symptoms of hypoglycemia or hyperglycemia
    • monitor body weight over time
    • may cause decreased inorganic phosphates, potassium, and magnesium
    • monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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    4 mins
  • Insulin – Intermediate Acting (NPH)
    Aug 2 2023

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    Generic Name

    Insulin NPH

    Trade Name

    Humulin N, Novolin N

    Indication

    hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

    Action

    stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
    prevents breakdown of fat and protein

    RouteOnsetPeakDurationSubcutaneous1-2 hr4-12hr18-24hr

    Therapeutic Class

    antidiabetics, hormones

    Pharmacologic Class

    pancreatics

    Nursing Considerations

    • assess for symptoms of hypoglycemia or hyperglycemia
    • monitor body weight over time
    • may cause decreased inorganic phosphates, potassium, and magnesium
    • monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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    4 mins