A beachside interview with Michael Hofman to hear all the PSMA theranostic highlights at ASCO this year! Yes we left our suburban studio in Melbourne and wandered down to St Kilda beach to track down Michael for a beer and a chat. Even in mid-Winter we enjoyed sitting out in a beachside shack at the Beachcomber Cafe and Beach Bar.
Michael shot some great interviews in Chicago with top clinicians in Nuclear Medicine including Bastiaan Privé, Louise Emmet, Jeremie Calais, Urologist Alberto Briganti, and Medical Oncologist Rana McKay. Great multidisciplinary perspectives on the Bullseye trial, Violet, Enza-P plus much more. Including a chat about the great promise of CAIX in renal cancer.



With your usual hosts, Renu Eapen and Declan Murphy

Enjoy the beachside chat even more on our YouTube channel

GU Cast Conference Highlights are supported by our Gold Partners, Bayer China.

Links:
Beachside Bar, St Kilda

What is Histolog?? Well, now that intra operative margin assessment is a such a hot topic in prostate cancer surgery after the Neurosafe RCT read-out, we thought we would dive into one of the other new technologies for doing something similar, but without the pragmatic challenges of frozen section. The idea is to assess the surgical margin of the prostate at the time of surgery to improve nerve sparing and sexual function for patients.

We are joined by Professor Greg Shaw (University College London, UK), PI of the Neurosafe Proof trial, which we already featured following their Lancet Oncology paper in March 2025, and our colleague Professor Nathan Lawrentschuk (Peter MacCallum Cancer Centre, AUS), who is leading a study of the Histolog device here in Melbourne. We chat first about Neurosafe and why intra-operative margin assessment is important, and then dive into Histolog which Greg has some experience with.

Histolog uses confocal laser microscopy to assess the prostate specimen at the time of surgery, with a similar principle to frozen section analysis as used in the Neurosafe technique. However Histolog offers a lot more convenience and removes some of the practical barriers we face with frozen section, which are barriers to implementation. But is it as good as frozen section? Join your usual hosts Declan Murphy and Renu Eapen to find out more.

Many thanks to our Silver Partners, Device Technologies, who are distributing the Histolog technology here in Australia, and to Samantree who are the manufacturers of the Histolog device.

This episode better enjoyed on our YouTube channel (if you don't mind some surgical scenes)!

Links
Previous GU Cast on Neurosafe with Greg Shaw and colleagues
Histolog device manufacturer website

A wonderful meandering chat with Ketan Badani (Urologist, Mt Sinai, NYC)! We took him for a wine tour in the Yarra Valley, stopping for a pod chat at Rochford Winery about screening for prostate cancer in older men, plus a great tour around Healesviile Sanctuary to introduce Ketan to some Australian wildlife. Then back in Melbourne we had another chat, this time a bit of future-gazing about the future of surgery, and Declan and Ketan trade tales about EMR (that's Electronic Medical Record) delinquency.

Ketan was visiting Melbourne as a guest of Device Technologies to speak at the Epworth Healthcare Robotic Urology Masterclass. And what a great guest he was!

With your usual hosts Renu Eapen and Declan Murphy. Thanks to our fantastic guide Trish at Healesville Sanctuary, and Beatrice who looked after us at Rochford Winery.

This one much better enjoyed on our YouTube channel!

Links:
Rochford Winery
Healesville Sanctuary