Current Treatment Approaches for Patients with Cold Agglutinin Disease
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Current Treatment Approaches for Patients with Cold Agglutinin Disease
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- Treatment goals should be to improve anemia by increasing Hb levels, avoid transfusion, improve circulatory symptoms caused by cold temperatures and reduce inflammatory symptoms
- There are a number of non-pharma treatment options, including thermal protection and cold avoidance and transfusions (avoid cold transfusions)
- Corticosteroids should not be used to treat CAD
- There are several first-line and second-line pharmaceutical treatment strategies, including Rituximab monotherapy, Rituximab-Bendamustine and Rituximab-Fludarabine combination therapies and Bortezomib monotherapy
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