Many people follow all the right steps—eating a healthy diet, exercising consistently, and achieving a caloric deficit—yet the scale refuses to budge. Why? The answer often lies in hormonal imbalance, metabolic dysfunction, and food noise.

Weight loss isn’t just about "eating less and moving more." Underlying issues like insulin resistance, low testosterone, thyroid dysfunction, and even gut health can dramatically impact results. The body's metabolic adaptation to weight loss can slow progress, and factors like sleep, stress, and cortisol play a bigger role than many realize.

Additionally, new therapies such as GLP-1 receptor agonists (like Semaglutide and Tirzepatide) are transforming weight management, not just by reducing appetite but also reducing food addiction.

In this episode, Dr. Huff and Dr. Weston take a deep dive into:

• The common hormonal roadblocks to weight loss
• The importance of metabolic health and how to assess it
• The truth about GLP-1 medications—who they help, how they work, and their long-term impact

If you've ever felt stuck in your weight loss journey despite doing everything “right,” this episode is for you.

• Continuous Glucose Monitoring – https://www.levelshealth.com
• Precision Hormone Testing – https://www.dutchtest.com
• Pendulum Probiotics (Akkermansia for Gut Health) – https://www.pendulumlife.com
• Why Zebras Don't Get Ulcers—Book by Robert Sapolsky: https://www.amazon.com/Why-Zebras-Dont-Ulcers-Third/dp/0805073698

Dr. Marguerite Weston combines a robust foundation of conventional medicine experience with the best contemporary functional medicine practices for a fresh and effective approach to optimizing health. She addresses discomfort at its root cause and provides long-term solutions that allow you to take control of your life again.

As a functional medicine patient herself, Dr. Weston believes that your discomfort, pain and anxieties are valid. She uses your personal input and diagnostic testing results to finally deliver the answers about your health you’ve been looking for.

With more than 17 years of experience in sports medicine and family practice, Dr. Weston has spent her entire career uncovering medical mysteries for her patients. As the Director of Functional Medicine at Donaldson, she integrates the strengths of both modern medicine and more holistic, natural methods to create hyper-personalized treatment plans for each patient. This combination unlocks a world of therapeutic potential — a reality that results in elevated well-being and an improvement in your overall health.

🔹 Follow Dr. Weston: @functionalmed
🔹 Learn more: Donaldson Plastic Surgery & Wellness

✔ Test, Don’t Guess – If you’re struggling with weight loss despite doing “all the right things”, an in depth hormonal assessment is warranted.

✔ Metabolic Health Matters – Assess for insulin resistance using the HOMA-IR calculator. When combined with expert interpretation, a continuous glucose monitor (CGM) can be insightful.

✔ Consider GLP-1 Medications If Indicated – For certain individuals struggling to lose weight, GLP-1 receptor agonists can be a game-changer, but should not replace appropriate nutrition and exercise.

Work with me: Premier Cardiovascular Health

Facebook: https://www.facebook.com/chris.huff.9480

Instagram: @hufcm

Disclaimer: The information provided in this podcast is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before making any decisions about your health or medical treatment.