Viroids & Virusoids: Nature’s Own mRNA
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Viroids & Virusoids: Nature’s Own mRNA
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About this listen
Messenger RNA (mRNA) has become a key therapeutic modality. Propelled into the spotlight by the COVID-19 pandemic, vaccines are only the tip of the iceberg: there’s an mRNA revolution on the horizon.
But long before mRNA was thought of as a potential therapeutic drug, nature devised its own transmissible messenger RNA: viroids and virusoids. By studying the mechanisms of these small, naked RNAs, we can learn to increase the efficiency of mRNA.
In his latest book, Dr. William Haseltine explores the world of viroids and virusoids in full detail: from their potential origins in the primordial soup —roughly three to four billion years ago— to the diseases they cause and everything in between. Each step along the way is ripe with implications for fields as diverse as biomedicine and agriculture. In addition to highlighting potential futures for mRNA, the book also discusses how virusoids can help us understand and address the fatal human disease of hepatitis D.