Dr. Erica Rosen is perplexed when she sees a young Chinese girl with blue eyes in her San Francisco pediatrics clinic. The girl's mother, Ting, is secretive, and Erica suspects she has entered the country illegally. Later, Erica encounters Ting's son and discovers he has an unusual mutation. Erica learns that Ting's children underwent embryonic stem cell gene editing as part of a secret Chinese government-run program.

A cop lies dying beneath the blistering Arizona sun - a local lawman who may well have become the next sheriff of Cochise County. The police brass claim that Andy Brady was dirty, and that his shooting was a suicide attempt. Joanna Brady, his devoted wife and mother of their nine-year-old daughter, knows a cover-up when she hears one...and murder when she sees it.

Madison Rivera lands the internship of a lifetime working for Judge Kathryn Conroy. But Madison has a secret that could destroy her career. Her troubled younger brother Danny has been arrested, and Conroy is the judge on his case. When Danny goes missing after accusing the judge of corruption, Madison’s quest for answers brings her deep into the judge’s glamorous world. Is Kathryn Conroy a mentor, a victim, or a criminal? Is she trying to help Madison or use her as a pawn? And why is somebody trying to kill her?

Mickey Gibson, single mother and former detective, leads a hectic life similar to that of many moms: juggling the demands of her two small children with the tasks of her job working remotely for ProEye, a global investigation company that hunts down wealthy tax and credit cheats. When Mickey gets a call from a colleague named Arlene Robinson, she thinks nothing of Arlene’s unusual request for her to go inventory the vacant home of an arms dealer who cheated ProEye’s clients and fled.

CIA Black Ops agent John Smith is on his latest assignment in London. Little does he know - it'll be his last. Barely surviving an attack on his life, Smith lays low for six months until he returns to the United States. His flight is strangely diverted to Philadelphia where he meets a mysterious stranger who knows all about his past and recruits him for a job. Needing a new identity, Smith becomes Michael Recker. He then tries to prevent bad things happening to innocent people while also interacting with the city's different crime factions.

Angela's graduate school days at MIT come to an abrupt end when she uses her hacking skills on another student's computer. Yet her mentor, Eve Abajian, arranges a new beginning for her - as an intern in FBI's Boston field office. Her new supervisor, Assistant Special Agent in Charge William Keats, one of only two agents in the Northeast to make his rank before the age of 30, sees in Angela a fellow prodigy. But Angela's skills come with a natural curiosity, which is also a dangerous liability.

When talented journalist Penelope “Casey" Harrison starts to research a piece about the #MeToo movement that includes an incident in her own life that she has been trying to put out of her mind for years, she does not realize the young man who drugged and assaulted her at a fraternity house party in college is now a wealthy, powerful industrialist on the eve of a merger that will make him a billionaire - and who will do anything, even murder, to cover his tracks.

Lieutenant Abby Mullen is no stranger to crisis. As the hostage negotiation instructor for the NYPD, she deals with worst-case scenarios every day. Nothing fazes her anymore. That all changes when she gets a call from Eden Fletcher, a fellow survivor of the infamous Wilcox cult. The two haven’t spoken since the night of a tragic, fiery massacre, when their paths diverged. But now Eden needs Abby’s help: someone has kidnapped her son and is demanding a $5 million ransom. As Abby throws herself into the case, she can’t help but wonder why the kidnapper has targeted Eden.

After her rescue of nearly 50 kidnapped children made international headlines, Amara Alvarez gets what she's worked for: a transfer to San Antonio's Homicide Division. Reality sets in quickly, though, as her first case, the suspicious death of a teenager at a crowded local water park, brings chaos to her personal life. As the investigation moves forward, and she increases the pressure on the suspects, Amara finds herself under attack by cybercriminals. Her every move is being potentially watched online, and she's forced to resort to unconventional methods to find the killer.

Three years ago, a collision between a fast-moving freight train and a school bus full of kids led to devastation and grief on an unimaginable scale. But a fresh clue leads San Antonio police detective Amara Alvarez to the unlikely conclusion that one of the children may still be alive. If she's correct, everything law enforcement believes about the accident is a lie.

When police stop Dustin Webb with a warrant to search his trunk, he knows there’s been a mistake. He’s former military and owns a security firm. But he’s horrified when the officers find explosives, and he can’t fathom how they got there. Criminal attorney Jamie Powell was Dustin’s best friend growing up. They haven’t spoken since he left for basic training, but she’s the first person he thinks of when he’s arrested. Jamie knows she’s putting her career on the line by defending an accused terrorist, but she’d never abandon him.

Quantum physicist Matt Bronik is suffering from strange, violent seizures that medical science seems powerless to explain - much to the consternation of his wife, Brigid. Matt doesn't think these fits could be related to his research, which he has always described as benign and esoteric. That, it turns out, is not quite true: Matt has been prodding the mysteries of the quantum universe, with terrible repercussions for his health. And perhaps even for humanity as a whole.

After her messy divorce, Angelina Bonaparte refuses to let any man hold her back. She’s even opened a private eye practice to help other victims of relationships gone sour. So when she crosses paths with a detective who believes a crime scene is no place for a woman, she sets out to change his mind.

Parker DuPont is a family man, with a wife, three children, and sister. As happens to many men Parker’s age, he faces the mid-life thing, and decides he wants to hang his own shingle, rather than spend the next 20-plus years as a St. Petersburg police detective. Private investigator sounds very appealing, and so off he goes into the private world to become his own boss. Welcome to his world.

It was one dark night that brought Damon Wolfe and Sophie Parker together. They were two tortured souls, looking for escape, and they weren't supposed to see each other ever again...Four years later, Sophie's FBI father, who is also Damon's mentor, is killed in a suspicious car crash after leaving Sophie a cryptic message to trust no one from the agency. When Damon shows up looking for her, she isn't sure if he's friend or enemy, but she knows he could easily rip apart what is left of her heart.