In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

Ken Holmes worked in the Marin County Coroner's Office for 36 years, starting as a death investigator and ending as the three-term, elected coroner. As he grew into the job - which is different from what is depicted on television - Holmes learned a variety of skills, from finding hidden clues at death scenes, interviewing witnesses effectively, managing bystanders and reporters, preparing testimony for court, to notifying families of a death with sensitivity and compassion.

From the New York Times best-selling author of Seven Brief Lessons on Physics, The Order of Time, and Helgoland, a closer look at the mind-bending nature of the Universe. What are the elementary ingredients of the world? Do time and space exist? And what exactly is reality? Theoretical physicist Carlo Rovelli has spent his life exploring these questions. He tells us how our understanding of reality has changed over the centuries and how physicists think about the structure of the Universe today.

Hallucinations don’t belong wholly to the insane. Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. Here Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all.

Today it is known as Roosevelt Island. In 1828, when New York City purchased this narrow, two-mile-long island in the East River, it was called Blackwell's Island. There, over the next hundred years, the city would build a lunatic asylum, prison, hospital, workhouse, and almshouse. Stacy Horn has crafted a compelling and chilling narrative told through the stories of the poor souls sent to Blackwell's, as well as the period's city officials, reformers, and journalists (including the famous Nellie Bly). Damnation Island re-creates what daily life was like on the island....

Bestselling true-crime master Harold Schechter explores the real-life headline-making psychos, serial murderers, thrill-hungry couples, and lady-killers who inspired a century of classic films.

Leonard Mlodinow, the best-selling author of The Drunkard’s Walk and coauthor of The Grand Design (with Stephen Hawking), gives us a startling and eye-opening examination of how the unconscious mind shapes our experience of the world and how, for instance, we often misperceive our relationships with family, friends, and business associates, misunderstand the reasons for our investment decisions, and misremember important events.

Mama's Last Hug opens with the dramatic farewell between Mama, a dying 59-year-old chimpanzee matriarch, and biologist Jan Van Hooff. This heartfelt final meeting of two longtime friends offers a window into how deep and instantly recognizable these bonds can be. So begins Frans de Waal's whirlwind tour of new ideas and findings about animal emotions, based on his renowned studies of the social and emotional lives of chimpanzees, bonobos, and other primates.

What is the nature of space and time? How do we fit within the universe? How does the universe fit within us? There's no better guide through these mind-expanding questions than acclaimed astrophysicist and best-selling author Neil deGrasse Tyson. But today, few of us have time to contemplate the cosmos. So Tyson brings the universe down to Earth succinctly and clearly, with sparkling wit, in digestible chapters consumable anytime and anywhere in your busy day.

Ryland Grace is the sole survivor on a desperate, last-chance mission - and if he fails, humanity and the Earth itself will perish. Except that right now, he doesn't know that. He can't even remember his own name, let alone the nature of his assignment or how to complete it. All he knows is that he's been asleep for a very, very long time. And he's just been awakened to find himself millions of miles from home, with nothing but two corpses for company.

And a Bottle of Rum tells the raucously entertaining story of America as seen through the bottom of a drinking glass. With a chapter for each of 10 cocktails, Wayne Curtis reveals that the homely spirit once distilled from the industrial waste of the exploding sugar trade has managed to infiltrate every stratum of New World society. Curtis takes us from the taverns of the American colonies, to the plundering pirate ships off the coast of Central America, to the watering holes of pre-Castro Cuba, and to the kitsch-laden tiki bars of 1950s America.

In the 21st century, humanity is reaching new heights of scientific understanding - and at the same time appears to be losing its mind. How can a species that developed vaccines for COVID-19 in less than a year produce so much fake news, medical quackery, and conspiracy theorizing? Pinker rejects the cynical cliché that humans are an irrational species - cavemen out of time saddled with biases, fallacies, and illusions.

In Four Lost Cities, acclaimed science journalist Annalee Newitz takes listeners on an entertaining and mind-bending adventure into the deep history of urban life. Investigating across the centuries and around the world, Newitz explores the rise and fall of four ancient cities, each the center of a sophisticated civilization: the Neolithic site of Çatalhöyük in Central Turkey, the Roman vacation town of Pompeii in Italy, the medieval megacity of Angkor in Cambodia, and the indigenous metropolis Cahokia, which stood beside the Mississippi River where East St. Louis is today.

The importance of money in our lives is readily apparent to everyone - rich, poor, and in between. However grudgingly, most of us accept the expression "money makes the world go round" as a universal truth. We are all aware of the power of money - how it influences our moods, compels us to take risks, and serves as the yardstick of success in societies around the world. Yet because we take the daily reality of money so completely for granted, we seldom question how and why it has come to play such a central role in our lives.

Filled to the brim with far-out facts, this wickedly informative narrative from the author of National Geographic's popular Gory Details blog takes us on a fascinating journey through an astonishing new reality. Blending humor and journalism in the tradition of Mary Roach, acclaimed science reporter Erika Engelhaupt investigates the gross, strange, and morbid absurdities of our bodies and our universe.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

We've all had to make decisions in our lives about what to keep and what to toss—habits, attitudes, friends, even homes. In this new collection of essays, Elizabeth Passarella explores the ups and downs of moving forward—both emotionally and logistically—with her welcome candor and sense of humor that listeners have come to love. It Was an Ugly Couch Anyway will make listeners laugh, cry, and feel a little less alone as they navigate their own lives that are filled with uncertainty, change, and things beyond their control.

As the country's top forensic pathologist, Dr Richard Shepherd has spent a lifetime uncovering the secrets of the dead. When death is sudden or unexplained, it falls to Shepherd to establish the cause. Each post-mortem is a detective story in its own right - and Shepherd has performed over 23,000 of them. Through his skill, dedication and insight, Dr Shepherd solves the puzzle to answer our most pressing question: how did this person die?

In The WEIRDest People in the World, Joseph Henrich draws on cutting-edge research in anthropology, psychology, economics, and evolutionary biology to explore these questions and more. He illuminates the origins and evolution of family structures, marriage, and religion, and the profound impact these cultural transformations had on human psychology. Mapping these shifts through ancient history and late antiquity, Henrich reveals that the most fundamental institutions of kinship and marriage changed dramatically under pressure from the Roman Catholic Church.

Dame Sue Black is an internationally renowned forensic anthropologist and human anatomist. She has lived her life eye to eye with the Grim Reaper, and she writes vividly about it in this book, which is part primer on the basics of identifying human remains, part frank memoir of a woman whose first paying job as a schoolgirl was to apprentice in a butcher shop, and part no-nonsense but deeply humane introduction to the reality of death in our lives. It is a treat for CSI junkies, murder mystery and thriller fans, and anyone seeking a clear-eyed guide to a subject that touches us all.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

Every one of us contains a billion times more atoms than all the grains of sand in the earth’s deserts. If you weigh 150 pounds, you’ve got enough carbon to make 25 pounds of charcoal, enough salt to fill a saltshaker, enough chlorine to disinfect several backyard swimming pools, and enough iron to forge a 3-inch nail. But how did these elements combine to make us human?

Professor of psychiatry Elyn R. Saks writes about her struggle with schizophrenia in this unflinching account of her mental illness. In The Center Cannot Hold, Saks draws readers into a nightmare world of medications, a misguided health-care system, and social stigmas. But she would not be defeated. With a strength and force of will that most can only imagine, Saks reclaimed her life and went on to achieve great success.

Based on the rare and until now overlooked journal of a Renaissance-era executioner, the noted historian Joel F. Harrington's The Faithful Executioner takes us deep inside the alien world and thinking of Meister Frantz Schmidt of Nuremberg, who, during 45 years as a professional executioner, personally put to death 394 individuals and tortured, flogged, or disfigured many hundreds more. But the picture that emerges of Schmidt from his personal papers is not that of a monster. Could a man who routinely practiced such cruelty also be insightful?