Has the mystery of ME/CFS finally been solved?

For decades, Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) has remained a medical enigma—misunderstood, misdiagnosed, and often dismissed. But breakthrough research might finally be changing that.

In this accessible and hopeful guide, ME/CFS patient Patrick Ussher distills the groundbreaking work of Professors Klaus Wirth and Carmen Scheibenbogen, who have proposed a compelling unifying model of ME/CFS. This new understanding brings together multiple dysfunctions—low blood volume, microclots, mitochondrial damage, autoimmunity, and more—into one interconnected cycle. It may, at last, explain why so many suffer from post-exertional malaise, brain fog, and relentless fatigue.

More than just theory, this book discusses healing strategies:

• Breathing techniques to improve oxygenation
• Ancestral nutrition and gut repair
• Microclot treatments
• Blood-washing procedures like HELP Apheresis & Immunoadsorption
• The Perrin technique
• The strengths & limitations of neuroplasticity ('brain retraining')
• Promising future medications—especially the new ‘Mitodicure’ pill, which could become the first drug specifically for ME/CFS

Patrick also shares his own story of living with ME/CFS and what has helped him most—physically and emotionally. His goal is simple: to empower fellow patients with knowledge, practical tools, and renewed hope.

Whether you have ME/CFS or Long Covid, this book will help you understand your illness—and imagine a life beyond it.

Includes a foreword by Prof. Klaus Wirth who is developing the ‘Mitodicure’ pill.