When a mysterious tower appears in the skies over England, thirteen strangers are pulled from their lives to stand before it as a countdown begins. Above the doorway is one word: ASCEND. As a grieving teacher, a reclusive artist, and a narcissistic celebrity children's author lead the others in trying to understand why they've been chosen and what the tower is, it soon becomes clear the only way out of this for everyone . . . is up.

Inside the tony suburb of Scarsdale is New York’s worst-kept secret: The mob runs everything, and the Nicastro family is at the center. Seventeen-year-old Tasha Nicastro lives a life of glitz and glamour, but she has no idea her family harbors a dark truth. Tasha might look like your classic high school mean girl, but behind the designer clothes is a sharpshooter who knows how to bring anyone to their knees. The only person who has ever gotten under her skin is her former best friend, Leo Danesi, the youngest son of the Nicastro family’s rivals.

A carefree New England vacation is just what sixteen-year-old Lucia needs to chase her sadness away. At least, according to her mom, who whisks them away for the summer with her ridiculously wealthy new boyfriend. Nothing bad happens in Nantucket, a charming island with cobblestone streets and million-dollar cottages. But when Lucia stumbles upon the body of a teenage girl on a beach, the discovery reopens old wounds from her past. With the dead girl's identity a mystery, Lucia takes it upon herself to investigate and crosses paths with Selah and her pack of devil-may-care besties.

Cuban American Camila Núñez has always been afraid of the future. She’s been working hard to keep her anxieties in check, but with so many new experiences―her first queer love, trouble with her dog walking job, her mother’s judgments about her body, learning to drive, her father being too busy with work―there’s just so much to worry about. So when Camila’s best friend gives her a tarot card reading for her sixteenth birthday, she believes it when the cards predict terrible things to come. As the year unfolds, the cards seem to be spot-on―is her papi having an affair?

It’s spring of 2020 and Rachel Bloomstein—mother of three, recent divorcée, and Brooklynite—is stuck inside. But her newly awakened sexual desire and lust for a new life refuse to be contained. Leaning on her best friend Lulu to show her the ropes, Rachel dips a toe in the online dating world, leading to park dates with younger men, flirtations with beautiful women, and actual, in-person sex. None of them, individually, are perfect . . . hence her rotation. But what if one person could perfectly cater to all her emotional needs?

Olivia Becente was never supposed to have the gift. The ability to commune with the dead was the specialty of her sister, Naiche. But when Naiche dies unexpectedly and under strange circumstances, somehow Olivia suddenly can’t stop seeing and hearing from spirits. A few years later, she’s the most in-demand paranormal investigator in Denver. She’s good at her job, but the loss of Naiche haunts her. That’s when she hears from the Brown Palace, a landmark Denver hotel.

For decades, a dark force has terrorized the Languille Lake reservation. Only spoken of in whispers as "the sandman," he lurks in the Hidden Atlantis Lake Resort and Casino, the reservation's main attraction and source of revenue, leeching its patrons' dreams and ambitions and also preventing the ghosts that linger there from moving on. Fleeing a breakup, Marion Lafournier, a mid-twenties Ojibwe, seeks solace in the slot machine's siren song.

Sydney Wells should have died. She was supposed to die. She never expected, after years of waiting, to receive a heart transplant. Now, seventeen-year-old Sydney doesn’t know what to do with her life. Her daily routine consisted of staying indoors, eating heart-healthy foods, and posting about her transplant list experiences on TheWaitingList with her long-distance BFF (and heart failure buddy) Chloe. Now, Sydney latches onto the one thing that gives her meaning: learning as much as she can about the person whose heart she inherited.

Seventeen-year-old Caprice wants to piece her family back together now that her older brother has returned home, even as she resents that he ever broke them apart. Just as she starts to get a new footing—falling in love for the first time, uncertainly mending her traumatized relationship with her brother, completing the app that will win her a college scholarship and a job in tech—wildfires strike Sierra, her small California town, forcing her to reckon with a future that is impossible to predict.

As a combat medic, Lina LaSalle went to Iraq to save the lives of fellow soldiers. But when her convoy is attacked, she must set aside her identity as a healer and take a life herself. Although she is honored as a hero when she returns to the US, Lina cannot find her footing. She is stricken with PTSD and unsure of how to support her young son, Teó, a little boy with Tourette’s. As her attempts to self-medicate become harder to hide, Lina realizes she must do the toughest thing yet: ask for help.

Raised in Connecticut, adopted twins Drita and Petrit (aka Pete) had no connection to their Albanian heritage. Their lives were all about Barbie dolls, the mall, and roller skating at the local rink. Although they were inseparable during their childhood, their paths diverged once they became teenagers: Drita was a good girl with good manners who was going to attend a good college; Pete was a bad boy going nowhere fast. Even their twinhood was not enough to keep them together.

All the women in Piper’s family know their true love at first sight, complete with butterflies, heart eyes, and a gut instinct. The kind of fated love that lasts forever. Piper grew up with her ancestors' epic love stories repeated like fairy tales, and yearns for the day she’ll start her own. Already singled out in her family due to her physical disability, Piper collects a second strike against her when her parents announce their divorce, which convinces her family that she’s doomed.

Jane Pool likes her safe, suburban existence just fine. She has a house, a family, (an infuriating mother-in-law,) and a quiet-if-unfulfilling administrative job at the local college. Everything is wonderfully, numbingly normal. Yet Jane remains haunted by her past: her mercurial, absent mother, her parents’ secrets, and the act of violence that transformed her life.

At a passing glance, County Road 951 is an entirely unremarkable stretch of blacktop, a two-lane scar across the Cascade foothills of Central Oregon. But the road is known by another name, coined by locals who’ve had to clean up after all those scenic detours went horribly wrong: The Devil’s Driveway. When Livia and her long-time friends take the Driveway as a shortcut to a much-needed weekend getaway, what begins as a morning joyride quickly becomes anything but. Soon, they’re driving for their lives, pursued by a horror beyond anything they ever imagined.

Smithsonian archaeologist Rabbit Ward travels through time on sponsored expeditions to the past to secure precious artifacts moments before they are lost to history. Although exceptional at his job, Rabbit is not without faults. In a spectacular failure twenty years ago, he lost both the menorah of the second temple and his hot-headed mentee, Aaron. So, when new evidence reveals the menorah’s reappearance in 6th century Constantinople, Rabbit seizes the chance for redemption. But from the moment he arrives in the past, things start to go wrong.