Joel lives in a nursing home, and he’s not one bit happy about it. He hates being told when to eat, when to sleep, when to take his pills. He’s fed up with life and begins to plan a way out when his new roommate, a retired soap opera actor named Frank, moves in and turns the nursing-home community upside down.

Ruby Heartwood has always lived a life on the move. As a traveling psychic, she makes her living working at carnivals and festivals and circuses around New England. It's a life Ruby has made peace with - settling in one place has never been for her. She needs no one, and no one needs her. Until one night, when she is camped by the side of the road in her trusty Volkswagon "Westie" van, a fierce thunder and lightning storm erupts.

Single mom Skye Mitchell has sunk her last dime into a dream, owning the venerable, if run-down, LakeView Hotel in the Berkshire Hills. It's here where she believes she'll give her 14-year-old daughter, Cody, a better life. But being an innkeeper is more challenging than she imagined, and Cody still manages to fall in with the wrong crowd. In addition, Cody is keeping an earth-shattering secret that she's terrified to reveal.

Boston police officer Cooper Harrison never thought he'd go back to his hometown, Harmony Farms. But when his faithful K-9 partner Argos is killed in the line of duty, Cooper, caught in a spiral of trauma and grief, has nowhere else to turn. Jobless and on the verge of divorce, he accepts a offer for the position of dog officer in Harmony Farms, leaving the life he spent twenty years building behind. And so he finds himself back where he started. Where his father was once known as the town drunk and his brother outgrew juvenile delinquency to become a drug dealer.

Dr. Cyrus Mills returns to his hometown after inheriting his father's failing veterinary practice. Cyrus intends to sell the practice and get out of town as fast as he can, but when his first patient - a down-on-her-luck golden retriever named Frieda Fuzzypaws - wags her way through the door, life suddenly gets complicated. Cyrus gets caught up in a new community and its endearing residents, both human and animal. Sensing he may have misjudged the past, he begins to realize it's not just his patients that need healing.

A decade ago Special Forces warrior Jason Morgan parachuted into the Central American jungle on an anti-narcotics raid. He'd served with the famous Night Stalkers on countless such missions. This one turned out very different. Months later he regained consciousness in a US military hospital, with no memory of how he'd gotten there. The first words he heard were from his surgeon, telling him he would never walk again. The determined soldier responded, "Sir, yes, I will."

If there's been a theme in Justine Meade's life, it's loss. Her mother, her home, even her son. The one bright spot in her loss-filled life, the partner she could always count on, was Mack, her grey and black Sheltie – that is, until she is summoned back to her childhood home after more than twenty years away. Ed and Alice Parmalee are mourning a loss of their own. Seven years after their daughter was taken from them, they're living separate lives together. Dancing around each other, and their unspeakable heartbreak, unable to bridge the chasm left between them.

Aleen Cust has big dreams. And no one―not her family, society, or the law―will stop her. Born in Ireland in 1868 to an aristocratic English family, Aleen knows she is destined to work with animals, even if her family is appalled by the idea of a woman pursuing a veterinary career. Going against their wishes but with the encouragement of the guardian assigned to her upon her father’s death, Aleen attends the New Veterinary College in Edinburgh, enrolling as A. I. Custance to spare her family the humiliation they fear.

Through the haze of vodka and self-loathing, Hazel Roundtree saw the poor creature lying in a ditch. One brown eye. One blue. Covered in mud and crying from pain, the puppy was desperately trying to free itself from a hopeless situation. She almost kept walking by. She had her own problems, and besides...no one had ever stopped to help her. Hazel had no idea the dog would be her beginning, her second chance, the miracle she never saw coming.

Former Broadway dancer and current agoraphobic Billy Shine has not set foot outside his apartment in almost a decade. He has glimpsed his neighbors--beautiful manicurist Rayleen, lonely old Ms. Hinman, bigoted and angry Mr. Lafferty, kind-hearted Felipe, and nine-year-old Grace and her former addict mother, Eileen. But most of them have never seen Billy. Not until Grace begins to sit outside on the building's front stoop for hours every day, inches from Billy's patio.

Lewis Madigan is young, gay, out of work, and getting antsy when he’s roped into providing end-of-life care for his insufferable homophobic neighbor, Chester Wheeler. Lewis doesn’t need the aggravation, just the money. The only requirements: run errands, be on call, and put up with a miserable old churl no one else in Buffalo can bear. After exchanging barbs, bickering, baiting, and pushing buttons, Chester hits Lewis with the big ask. Lewis can’t say no to a dying wish.

Early 1900s London: Taken from his homeland, twelve-year-old Celestine spends most of the time locked away in the attic of a large house by the sea. The only time Celestine isn’t bound by confines of the small space is when he is acting as an unpaid servant to English explorer Sir Richard Babbington, As the years pass, he desperately clings on to memories of his family in Africa, even as he struggles to remember his mother’s face, and sometimes his real name . . .

An injured, young dog trudges the city streets, trembling from cold, from fear, from lack of food. Battered by the howling wind, he searches desperately for his lost family, yet day after day, week after week, all he ever finds is heartbreaking loneliness. But then, one magical spring morning....

The folks in the Kentucky Appalachians are scraping by. Coal mining and hardscrabble know-how are a way of life for these isolated people. But when Amanda Rye, a young widowed mother and traveling packhorse librarian, comes through a mountain community hit hard by the nation’s economic collapse, she brings with her hope, courage, and apple pie.

Pennsylvania, 1940s. The only life Brighton Friedrich has ever known is the one she has endured within the dreary walls of Riverside Home—the rural asylum where she was born. A nurse, Joann, has educated and raised Brighton, whose mother is a patient at the hospital. But Joann has also kept vital information from Brighton—secrets that if ever revealed would illuminate Brighton’s troubling past and the circumstances that confine her to Riverside.