Mia, the irreverent, hyperanalytical twenty-year-old daughter, has an explanation for everything—which is why she isn’t initially concerned when her father and younger brother Eugene don’t return from a walk in a nearby park. They must have lost their phone. Or stopped for an errand somewhere. But by the time Mia’s brother runs through the front door bloody and alone, it becomes clear that the father in this tight-knit family is missing and the only witness is Eugene, who has the rare genetic condition Angelman syndrome and cannot speak.

The only child of a single mother, Nina has her life just as she wants it: a job in a bookstore, a kick-butt trivia team, a world-class planner and a cat named Phil. If she sometimes suspects there might be more to life than reading, she just shrugs and picks up a new book. When the father Nina never knew existed suddenly dies, leaving behind innumerable sisters, brothers, nieces, and nephews, Nina is horrified. They all live close by! They're all - or mostly all - excited to meet her! She'll have to Speak. To. Strangers. It's a disaster!

Abbi Hope Goldstein is like every other teenager, with a few smallish exceptions: Her famous alter ego, Baby Hope, is the subject of internet memes, she has asthma, and sometimes, people spontaneously burst into tears when they recognize her. Abbi has lived almost her entire life in the shadow of the terrorist attacks of September 11. On that fateful day, she was captured in what became an iconic photograph: In the picture, Abbi (aka "Baby Hope") wears a birthday crown and grasps a red balloon; just behind her, the South Tower of the World Trade Center is collapsing.

When Danny discovers a taped-up box in his father's closet filled with old letters and a file on a powerful Silicon Valley family, he realizes there's much more to his family's past than he ever imagined. Danny has been an artist for as long as he can remember, and it seems his path is set, with a scholarship to RISD and his family's blessing to pursue the career he's always dreamed of. Still, contemplating a future without his best friend, Harry Wong, by his side makes Danny feel a panic he can barely put into words.

Laya Marston’s husband, Cameron, a daredevil enthusiast, was the complete opposite of her, ready and willing to dive off a cliff-face or parachute across a canyon - and Laya loved him for it. But she was different: pragmatic, regimented, devoted to her career and to supporting Cameron from the sidelines of his death-defying feats. Opposites attract, right? But when Cameron dies tragically, Laya becomes lost in denial, living in the delusion that Cameron will come back to her.

Everything about Jessie is wrong. At least that's what it feels like during her first week of junior year at her new ultra-intimidating prep school in Los Angeles. Just when she's thinking about hightailing it back to Chicago, she gets an email from a person calling themselves Somebody/Nobody (SN for short), offering to help her navigate the wilds of Wood Valley High School. Is it an elaborate hoax? Or can she rely on SN for some much-needed help?

Everyone knows everyone in the tiny town of Bourne, but the Mitchell triplets are especially beloved. Mirabel is the smartest person anyone knows, and no one doubts it just because she can’t speak. Monday is the town’s purveyor of books now that the library’s closed - tell her the book you think you want, and she’ll pull the one you actually do from the microwave or her sock drawer. Mab’s job is hardest of all: get good grades, get into college, get out of Bourne.

Karina Chopra would have never imagined becoming friends with the boy next door - after all, they've avoided each other for years and she assumes Chris is just like the boys he hangs out with, who she labels a pack of hyenas. Then Karina's grandfather starts tutoring Chris, and she discovers he's actually a nice, funny kid. But one afternoon something unimaginable happens - the three of them are assaulted by a stranger who targets Indian-American Karina and her grandfather because of how they look. Her grandfather is gravely injured and Karina and Chris vow not to let hate win.

Four years ago, 19-year-old Travis Brown made a choice: to raise his newborn daughter on his own. While most of his friends were out partying and meeting girls, Travis was at home, changing diapers and worrying about keeping food on the table. But he's never regretted his decision. Bella is the light of his life. The reason behind every move he makes. And so far, she is fed. Cared for. Safe. But when Travis loses his construction job and his home, the security he's worked so hard to create for Bella begins to crumble....

While her humanitarian husband Liam has been digging wells in Africa, Mara Jacobs has been struggling. She knows she's supposed to feel a warm glow that her husband is nine time zones away, caring for widows and orphans. But the reality is that she is exhausted. Then Liam's three-year absence turns into something more, changing everything and plunging her into a sunless grief. As Mara struggles to find her footing, she discovers that even when hope is tenuous, faith is fragile, and the future is unknown, we can be sure we are not forgotten...or unloved.

Jill MacSweeny just wishes everything could go back to normal. But ever since her dad died, she's been isolating herself from her boyfriend, her best friends - everyone who wants to support her. And when her mom decides to adopt a baby, it feels like she's somehow trying to replace a lost family member with a new one.

Ava, CJ, Jordan, and Martha (listed in alphabetical order out of fairness) have been friends since kindergarten. Now they're in their senior year, facing their biggest fears about growing up and growing apart. But there's more than just college on the horizon. One of these girls is destined to become the president of the United States. The mystery, of course, is which girl gets the gig.

To the outside world, beloved advice columnist Lane Meckler has all the answers. What no one knows is that she also has a secret: her life is a disaster, and it's just gotten worse. Her husband, whom she was planning to leave, has died in a freak accident. Her six-year-old son, Henry, has stopped speaking to everyone but her. Lane's solution? Move. Growing up, that was what her family did best.

It's good to be Chloe Wynn Berringer - she has it all - money, privilege, and a ticket to the college of her dreams. Or at least she did until the FBI came knocking on her front door, guns at the ready, and her future went up in smoke. Now her B-list celebrity mother is under arrest in a massive college admissions bribery scandal, and Chloe might be the next one facing charges. The public is furious, the headlines are brutal, and the US attorney is out for blood.

Cassandra McMurtrey has the best parents a girl could ask for; they’ve given Cass a life she wouldn’t trade for the world. She has everything she needs - but she has questions, too. Like, to know who she is. Where she came from. Questions her adoptive parents can’t answer, no matter how much they love her. But 18 years ago, someone wrote Cass a series of letters. And they may just hold the answers Cass has been searching for.