It's America in 1962. Slavery is legal once again. The few Jews who still survive hide under assumed names. In San Francisco, the I Ching is as common as the Yellow Pages. All because some twenty years earlier the United States lost a war - and is now occupied by Nazi Germany and Japan.

Jason Taverner—world-famous talk show host and man-about-town—wakes up one day to find that no one knows who he is—including the vast databases of the totalitarian government. And in a society where lack of identification is a crime, Taverner has no choice but to go on the run with a host of shady characters, including crooked cops and dealers of alien drugs. But do they know more than they are letting on? And just how can a person's identity be erased overnight?

Ragle Gumm has a unique job: every day he wins a newspaper contest. And when he isn’t consulting his charts and tables, he enjoys his life in a small town in 1959. At least, that’s what he thinks. But then strange things start happening. He finds a phone book where all the numbers have been disconnected, and a magazine article about a famous starlet he’s never heard of named Marilyn Monroe. Plus, everyday objects are beginning to disappear and are replaced by

Bob Arctor is a dealer of the lethally addictive drug Substance D. Fred is the police agent assigned to tail and eventually bust him. To do so, Fred takes on the identity of a drug dealer named Bob Arctor. And since Substance D, which Arctor takes in massive doses, gradually splits the user's brain into two distinct, combative entities, Fred doesn't realize he is narcing on himself.

On Mars, the harsh climate could make any colonist turn to drugs to escape a dead-end existence. Especially when the drug is Can-D, which transports its users into the idyllic world of a Barbie-esque character named Perky Pat. When the mysterious Palmer Eldritch arrives with a new drug called Chew-Z, he offers a more addictive experience, one that might bring the user closer to God. But in a world where everyone is tripping, no promises can be taken at face value.