For as long as we’ve studied human cognition, we’ve believed that our senses give us direct access to the world. What we see is what’s really there—or so the thinking goes. But new discoveries in neuroscience and psychology have turned this assumption on its head. What if rather than perceiving reality passively, your mind actively predicts it?

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

Over two millennia ago, the prescient insights of Anaximander paved the way for cosmology, physics, geography, meteorology, and biology, setting in motion a new way of seeing the world. His legacy includes the revolutionary ideas that the Earth floats in a void, that animals evolved, that the world can be understood in natural rather than supernatural terms, and that universal laws govern all phenomena. In this elegant work, the renowned theoretical physicist Carlo Rovelli brings to light the importance of Anaximander’s overlooked influence on modern science

Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.

Derek Parfit (1942–2017) is the most famous philosopher most people have never heard of. Widely regarded as one of the greatest moral thinkers of the past hundred years, Parfit was anything but a public intellectual. Yet his ideas have shaped the way philosophers think about things that affect us all: equality, altruism, what we owe to future generations, and even what it means to be a person. In Parfit, David Edmonds presents the first biography of an intriguing, obsessive, and eccentric genius.

Virtual reality is genuine reality; that’s the central thesis of Reality+. In a highly original work of “technophilosophy,” David J. Chalmers gives a compelling analysis of our technological future. He argues that virtual worlds are not second-class worlds, and that we can live a meaningful life in virtual reality. We may even be in a virtual world already.

Nothing in the universe is more complex than life. Throughout the skies, in oceans, and across lands, life is endlessly on the move. In its myriad forms—from cells to human beings, social structures, and ecosystems—life is open-ended, evolving, unpredictable, yet adaptive and self-sustaining. Complexity theory addresses the mysteries that animate science, philosophy, and metaphysics: how this teeming array of existence, from the infinitesimal to the infinite, is in fact a seamless living whole and what our place, as conscious beings, is within it.

For all of neuroscience's advances, we've made little progress on its biggest question: How do simple cells in the brain create intelligence? Jeff Hawkins and his team discovered that the brain uses map-like structures to build a model of the world - not just one model, but hundreds of thousands of models of everything we know. This discovery allows Hawkins to answer important questions about how we perceive the world, why we have a sense of self, and the origin of high-level thought.

The world is never finished catching up with Vaclav Smil. In his latest and perhaps most digestible book, Invention and Innovation, the prolific author—a favorite of Bill Gates—pens an insightful and fact-filled jaunt through the history of human invention. Impatient with the hype that so often accompanies innovation, Smil offers in this book a clear-eyed corrective to the overpromises that accompany everything from new cures for diseases to AI.

A major new biography of J Edgar Hoover that draws from never-before-seen sources to create a groundbreaking portrait of a colossus who dominated half a century of American history and planted the seeds for much of today's conservative political landscape.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

In What We Owe The Future, philosopher William MacAskill argues for longtermism, that idea that positively influencing the distant future is a key moral priority of our time. It’s not enough to reverse climate change or avert the next pandemic. We must ensure that civilization would rebound if it collapsed, counter the end of moral progress, and prepare for a planet where the smartest beings are digital, not human. If we set humanity’s course right, our grandchildren’s grandchildren will thrive, knowing we did everything to give them a world of justice, hope, and beauty.

The most trusted explainer of the most mind-boggling concepts pulls back the veil of mystery that has too long cloaked the most valuable building blocks of modern science. Sean Carroll, with his genius for making complex notions entertaining, presents in his uniquely lucid voice the fundamental ideas informing the modern physics of reality. In the tradition of the legendary Richard Feynman lectures presented sixty years ago, this book is an inspiring, dazzling introduction to a way of seeing that will resonate across cultural and generational boundaries for many years to come.

What does it mean to “be you” - that is, to have a specific, conscious experience of the world around you and yourself within it? There may be no more elusive or fascinating question. Historically, humanity has considered the nature of consciousness to be a primarily spiritual or philosophical inquiry, but scientific research is now mapping out compelling biological theories and explanations for consciousness and selfhood.

In The Universe in a Box, cosmologist Andrew Pontzen explains how physicists model the universe’s most exotic phenomena, from black holes and colliding galaxies to dark matter and quantum entanglement, enabling them to study the evolution of virtual worlds and to shed new light on our reality.