Far North Queensland, 1993: at 74, former cane farmer Grace Maud is feeling her age, and her isolation, and thinks the best of life may be behind her. Elsewhere in town, high school teacher Patricia has given up on her dreams of travel and adventure and has moved back home to look after her ageing parents, while cafe owner Dorothy is struggling to accept that she may never have the baby she and her husband so desperately want. Each woman has an unspoken need: reconnection. And that's how they find themselves at Orange Blossom House, surrounded by perfumed rainforest.

In a seaside suburb of NSW, housewife Theresa Howard takes up swimming. She wants to get fit; she also wants a few precious minutes to herself. So at sunrise each day she strikes out past the waves. From the same beach, the widowed Marie swims. With her husband gone, bathing is the one constant in her new life. After finding herself in a desperate situation, 26-year-old Leanne only has herself to rely on. She became a nurse to help others, even as she resists help herself. Elaine has recently moved from England.

It’s a warm, bright October afternoon, and Ozro Armstead walks out into the brilliant sunshine on his thirty-seventh birthday. At home, his wife Deborah and daughter Trinity prepare a surprise celebration; down the street, his brother waves as Oz heads back to his office after having lunch together. But he won’t make it to the party or even to his briefcase back at his desk. He's about to disappear.

Hollis Shaw, creator of the popular food blog, Hungry with Hollis, is shocked when her heart surgeon husband, Matthew, is killed in a one-car accident on a snowy morning. The cracks in Hollis’s perfect life—her strained marriage and her complicated relationship with her daughter, Caroline—grow deeper. So when Hollis hears about something called a “Five-Star Weekend”—one woman organizes a trip for her best friend from each phase of her life: her teenage years, her twenties, her thirties, and midlife—she decides to host her own Five-Star Weekend on Nantucket.

Kentucky, 1850. An enslaved groom named Jarret and a bay foal forge a bond of understanding that will carry the horse to record-setting victories across the South. When the nation erupts in civil war, an itinerant young artist who has made his name on paintings of the racehorse takes up arms for the Union. On a perilous night, he reunites with the stallion and his groom, very far from the glamor of any racetrack.

A kid walks into your bookstore and says to you, Guess what? I'm your son. The one you put up for adoption seventeen years ago. The one you never told anyone about. Surprise! His name is Matthew Walker, and he's come to spend the summer on the Cape with his parents. Why? Well, he wants to meet you before he heads off to college in the fall. Tiny detail—he didn't tell his adoptive parents about his plan. And while you hoped this day would come someday, you're so stunned, you actually faint.

Los Angeles, 1920s: Socialite Mirielle West's days are crowded with shopping, luncheons, and prepping for the myriad glittering parties she attends with her actor husband, Charlie. She's been too busy to even notice the small patch of pale skin on the back of her hand. Other than an occasional overindulgence in gin and champagne, which helps to numb the pain of recent tragedy, Mirielle is the picture of health. But her doctor insists on more tests, and Mirielle reluctantly agrees. The diagnosis - leprosy - is devastating and unthinkable.

In 1940s and ’50s America, polio is as dreaded as the atomic bomb. No one’s life is untouched by this disease that kills or paralyzes its victims, particularly children. Outbreaks of the virus across the country regularly put American cities in lockdown. Some of the world’s best minds are engaged in the race to find a vaccine. The man who succeeds will be a god.

Tessa O’Connor is tired of the high society lifestyle, and the pressure is on for her to marry a wealthy man. Fearful of becoming trapped in a life that would make her increasingly miserable, she decides to try the mail-order bride approach.

Berlin, 1930—When a wave of change sweeps a radical political party to power, Sofie von Meyer Rhodes’s academic husband benefits from the ambitions of its newly elected chancellor. Although Sofie and Jürgen do not share the social views growing popular in Hitler’s Germany, Jürgen’s position with its burgeoning rocket program changes their diminishing fortunes for the better. But as Sofie watches helplessly, her beloved Berlin begins to transform, forcing her to consider what they must sacrifice morally for their young family’s security, and what the price for their neutrality will be.

When Sarah meets Eddie, they connect instantly and fall in love. To Sarah, it seems as though her life has finally begun. And it's mutual: It's as though Eddie has been waiting for her, too. Sarah has never been so certain of anything. So when Eddie leaves for a long-booked vacation and promises to call from the airport, she has no cause to doubt him. But he doesn't call. Sarah's friends tell her to forget about him, but she can't. She knows something's happened - there must be an explanation.

My husband was not a monster. No matter what they say.... The day my husband, Michael, stepped in front of a lorry after being questioned by the police, my world fell apart. He was devoted to me and our six-year-old daughter. But they’d connected him to the disappearance of a young mother from our tiny village.

Bride-to-be Leona is thrilled to be on a mini-vacation in the pretty town of Pinecraft. Her girlfriends think she’s happy to be away from the stress of wedding planning; they have no idea that Leona’s real joy is in being away from her fiancé. Edmund is a good man and will make a decent husband...just not for Leona. The more time she spends with him and his overbearing ways, the less she wants to be his wife.

Every family has a story.... But for the Guinness family a happy ending looks out of reach. Olly and Mae's marriage is crumbling, their teenage daughter Evie is on a mission to self-destruct and their beloved Pops is dying of cancer. Their once strong family unit is slowly falling apart. But Pops has one final gift to offer his beloved family - a ray of hope to cling to. As his life's journey draws to a close, he sends his family on an adventure across Europe in a camper van, guided by his letters, his wisdom and his love.

Lucy is traveling by herself via train to Jacob’s Crossing to help care for her cousin Mattie, recently diagnosed with breast cancer. Trying to overcome the sudden death of her husband, she’s glad to get away and focus on someone else for a while.