
The Demon Under The Microscope
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Narrated by:
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Stephen Hoye
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By:
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Thomas Hager
About this listen
Sulfa saved millions of lives, among them, Winston Churchill's and Franklin Delano Roosevelt, Jr.'s, but its real effects have been even more far reaching. Sulfa changed the way new drugs were developed, approved, and sold. It transformed the way doctors treated patients. And it ushered in the era of modern medicine. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness.
A strange and vibrant story, The Demon Under the Microscope illuminates the colorful characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and central (though mistaken) idea that brought sulfa to the world. This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel.
©2006 Thomas Hager (P)2006 Tantor Media, Inc.Listeners also enjoyed...
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"Highly entertaining." (Publishers Weekly)
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Story
Who invented beds? When did we start cleaning our teeth? How old are wine and beer? Which came first: the toilet seat or toilet paper? What was the first clock? Every day, from the moment our alarm clock wakes us in the morning until our head hits our pillow at night, we all take part in rituals that are millennia old. Structured around one ordinary day, A Million Years in a Day reveals the astonishing origins and development of the daily practices we take for granted.
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Super interesting!
- By Brandon on 07-07-16
By: Greg Jenner
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Spark
- The Life of Electricity and the Electricity of Life
- By: Timothy J. Jorgensen
- Narrated by: Gary Tiedemann
- Length: 14 hrs and 34 mins
- Unabridged
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When we think of electricity, we likely imagine the energy humming inside our home appliances or lighting up our electronic devices - or perhaps we envision the lightning-streaked clouds of a stormy sky. But electricity is more than an external source of power, heat, or illumination. Life at its essence is nothing if not electrical.
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The best book on electricity.
- By Anonymous User on 01-10-22
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Poisons
- From Hemlock to Botox and the Killer Bean Calabar
- By: Peter Macinnis
- Narrated by: Stephen Hoye
- Length: 7 hrs and 36 mins
- Unabridged
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A wide-ranging and provocative look - teeming with little-known facts and engaging stories - at a subject of the direst interest. Poisons permeate our world. They are in the environment, the workplace, the home. They are in food, our favorite whiskey, medicine, well water. They have been used to cure disease as well as incapacitate and kill. They smooth wrinkles, block pain, stimulate, and enhance athletic ability. In this entertaining and fact-filled audiobook, science writer Peter Macinnis considers poisons in all their aspects. He recounts stories of the celebrated poisoners in history and literature....
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Poison, Americas past time
- By Sean’s tunes on 03-05-25
By: Peter Macinnis
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Symphony in C
- Carbon and the Evolution of (Almost) Everything
- By: Robert M. Hazen
- Narrated by: Paul Brion
- Length: 9 hrs and 42 mins
- Unabridged
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An enchanting biography of the most resonant - and most necessary - chemical element on Earth. Carbon. It's in the fibers in your hair, the timbers in your walls, the food that you eat, and the air that you breathe. It's worth billions as a luxury and half a trillion as a necessity, but there are still mysteries yet to be solved about the element that can be both diamond and coal. Where does it come from, what does it do, and why, above all, does life need it?
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There is a Caveat
- By Joseph L Contreras on 06-26-19
By: Robert M. Hazen
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Paradox
- The Nine Greatest Enigmas in Physics
- By: Jim Al-Khalili
- Narrated by: Matthew Waterson
- Length: 6 hrs and 54 mins
- Unabridged
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Throughout history, scientists have come up with theories and ideas that just don't seem to make sense. These we call paradoxes. The paradoxes Al-Khalili offers are drawn chiefly from physics and astronomy and represent those that have stumped some of the finest minds. With elegant explanations that bring the listener inside the mind of those who've developed them, Al-Khalili helps us to see that, in fact, paradoxes can be solved if seen from the right angle.
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Almost Useless
- By Michael on 06-19-19
By: Jim Al-Khalili
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Plagues, Pandemics and Viruses
- From the Plague of Athens to COVID-19
- By: Heather E. Quinlan
- Narrated by: Samara Naeymi
- Length: 14 hrs and 28 mins
- Unabridged
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It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.
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Some good info but
- By Dogs Land on 10-23-24
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Everything All at Once
- How to Unleash Your Inner Nerd, Tap into Radical Curiosity and Solve Any Problem
- By: Bill Nye
- Narrated by: Bill Nye
- Length: 12 hrs and 34 mins
- Unabridged
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Everything All at Once is an exciting, inspiring call to unleash the power of the nerd mindset that exists within us all. Nye believes we'll never be able to tackle our society's biggest, most complex problems if we don't even know how to solve the small ones. Step by step, he shows his listeners the key tools behind his everything-all-at-once approach: radical curiosity, a deep desire for a better future, and a willingness to take the actions needed to make it a reality.
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Bill Nye is awesome, but skip this one
- By Evan on 08-15-17
By: Bill Nye
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Quackery
- A Brief History of the Worst Ways to Cure Everything
- By: Lydia Kang, Nate Pedersen
- Narrated by: Hillary Huber
- Length: 10 hrs and 29 mins
- Unabridged
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What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.
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Computer-generated Narrator. Dated Humour.
- By Nemo on 12-28-18
By: Lydia Kang, and others
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Napoleon's Buttons
- 17 Molecules That Changed History
- By: Penny Le Couteur, Jay Burreson
- Narrated by: Laural Merlington
- Length: 11 hrs and 6 mins
- Unabridged
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Napoleon's Buttons is the fascinating account of 17 groups of molecules that have greatly influenced the course of history. These molecules provided the impetus for early exploration, and made possible the voyages of discovery that ensued. The molecules resulted in grand feats of engineering and spurred advances in medicine and law; they determined what we now eat, drink, and wear. A change as small as the position of an atom can lead to enormous alterations in the properties of a substance.
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Wish one of the authors would have read this book
- By A.J. on 03-09-12
By: Penny Le Couteur, and others
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Human Errors
- A Panorama of Our Glitches, from Pointless Bones to Broken Genes
- By: Nathan H. Lents
- Narrated by: L.J. Ganser
- Length: 7 hrs and 54 mins
- Unabridged
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We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.
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From Pointless Bones to Broken Genes to...Aliens?
- By Katy.LED on 12-04-18
By: Nathan H. Lents
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Miracle Cure
- The Creation of Antibiotics and the Birth of Modern Medicine
- By: William Rosen
- Narrated by: Rob Shapiro
- Length: 12 hrs and 10 mins
- Unabridged
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As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.
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Excellence
- By xar adelberg on 09-18-17
By: William Rosen
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Nine Lives
- Mystery, Magic, Death, and Life in New Orleans
- By: Dan Baum
- Narrated by: Jonathan Yen
- Length: 14 hrs and 24 mins
- Unabridged
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Nines Lives is a multivoiced biography of a dazzling, surreal, and imperiled city, told through the lives of nine unforgettable characters and bracketed by two epic storms: Hurricane Betsy, which transformed New Orleans in the 1960s, and Hurricane Katrina, which nearly destroyed it. Dan Baum brings this kaleidoscopic portrait to life, showing us what was lost in the storm and what remains to be saved.
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Do not miss if you're interested in New Orleans
- By Kelly on 03-22-18
By: Dan Baum
What listeners say about The Demon Under The Microscope
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- peter
- 03-06-09
Fascinating for the Science Buff
Thomas Hager has done extensive, detailed research and written his story in a concise style which makes him easy to follow. His characters are alive; the life of the scientist well described. I know of no other book which covers this subject matter; the development of the most commonly used medicines and some insight as to what life was like before this became available. Its relevance is brought to life by stories of two US Presidents' sons who became sick: one lived; one died. Absorbing detail in both cases.
Is it for everyone? Probably not. History buffs, science minded enthusiasts, medical students: I used it for some marvelous facts concerning the discovery of bacteria which parallels what is happening today in nanoscience. I can put that in PowerPoint in a second.
I have one comment for Audible, if they can do anything about it. The reader has a wonderful voice tone, speaks clearly and at the perfect speed for me. However, he has the annoying habit of dropping his tone at the end of just about every sentence or phrase, giving emphasis to the word in a way that lends sad reflection. Have you any idea how irritating this can be? I rather think it might be the same reader as ruined 'Slaughterhouse 5' for me, although the effect was a lot less intrusive in this book than there.
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14 people found this helpful
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- Rosalinda
- 04-17-15
So interesting
This is really a very good book . It surpassed my expectations. I am going to listen to it again . The narrator has a good voice
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2 people found this helpful
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- deborah
- 12-03-11
One of the Best of the Medical History Audiobooks
Well researched and narrated, this is the story of Sulfa, the pre-curser antibiotic to penicillin, and the stories of its discovery, use, and consequences for public health. Though lengthy, I finished it in two days. For those who are interested in the subject, or medical professionals, the book covers a class of drugs no longer studied. Wonderful book that had me checking wiki for further info on topics.
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2 people found this helpful
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- Calliope
- 10-02-16
Great book of history, medicine, and health
This is a very interesting and well-told story about something so common most people take it for granted -- antibiotics. But it's more than just the story of how the first medicine to fight bacterial infections was discovered, it's also the story of what life was like before antibiotics, how the Nazi's affected the development of medicine, and how even national boundaries affected what and how drugs were used around the world.
And it's written so well; it flows nicely and holds the readers' attention well.
There's a lot of dovetailing with Hager's "The Alchemy of Air" (also excellent, but with better narration), in that it occurs after that book but also involves the talented and innovative work of the men at Bayer in the early 20th century.
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2 people found this helpful
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- kate
- 11-09-10
Interesting topic, difficult to listen to
The subject and story are engrossing, but it was hard to listen to this narrator's overly dramatic inflections and his misproununciations. I gave up half way through.
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1 person found this helpful
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- Susan K Treiman
- 01-30-13
Interesting read
Fascinating tale that unfolds in the midst of wartime Germany. Although I cringed at some of the main characters' connections to the Nazis, I found the story interesting and revealing. Great delivery, too.
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1 person found this helpful
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- Amazon Customer
- 09-22-18
Fascinating Listen
Surprisingly easy listen with loads of interesting details. Paints the picture of early drug development and early Western medicine in a carefully thought out manner. The author does takes a few rabbit trails at times and, in my opinion, ended the book about a chapter too soon. Recommended read.
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- budsmom
- 07-01-13
Fascinating!
Would you recommend this audiobook to a friend? If so, why?
Yes, it was one of the best books I've ever read. A fascinating read!
What other book might you compare The Demon Under The Microscope to and why?
The Great Influenza because of the medical information they contain, written in an easy to understand, descriptive way.
What about Stephen Hoye’s performance did you like?
He was great. All the characters seem real and it was easy to keep them straight.
Any additional comments?
I was amazed at the lack of medical care as we know it in the US. In a country that was one of the world's leaders in inventions and innovations in the late 1800's - 1930's, it was appalling how ignorant the so called physicians were about disease, infections, and how to treat them properly. So many people died unnecessarily due to lack of sanitation and proper medicine. I was shocked to find out that doctors used many of the same methods that were used during the Middle Ages! No medical schools in the US were regulated or accredited; no research was done for anything and a man (no woman) could become a doctor with as little as 2 years of training. Almost all medical discoveries happened in Europe, Germany/France mostly. Here is where the first discoveries of molecules to produce antibiotics and antibacterials happened. This book not only explains very scientific ideas clearly, and in a way for anyone to understand.
This is the history of modern medicine as we know it today. It was not until 1937 that the first antibiotic was produced. The results amazed the world and changed the history of medicine. It is also the modern history of pharmacology. A fascinating read!
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- Cora Keegan
- 02-27-13
Great but 50% too big
What was the most interesting aspect of this story? The least interesting?
This story details how modern medicine was changed by the first antibiotics. A real eye opener especially about child birth infections and battle field surgery. The author details how dangerous and short life was before these drugs came out before world war 2. However, the book is too verbose. The details of some of the research are boring, for example in one point of the book they read off 10 minutes of numbers that were lab sample numbers, I let out a groan half way through that mind numbing detail. I took to pushing the skip 15 seconds ahead button a lot. Really about half this book could be edited out. It has a lot of details about unsuccessful experiments, some people's names and locations that don't real add much to the story.
Do you think The Demon Under The Microscope needs a follow-up book? Why or why not?
Nope, enough said.
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- Angie M.
- 06-28-15
The first miracle Drug and sacrifices to find it
Would you recommend this audiobook to a friend? If so, why?
Yes, but I would let them know it often goes very in depth in discussing the lives of the doctors and not everything is easy to listen to. This isn't a comfortable book at all times and a basic understanding of medical practices of the time is useful.
What was one of the most memorable moments of The Demon Under The Microscope?
There isn't one particular moment. There are so many people discussed in the book and their work was in concert.
Have you listened to any of Stephen Hoye’s other performances before? How does this one compare?
No this was my first. He did an excellent job in making the book interesting and giving his voice gravity when the subject matter became darker.
Was this a book you wanted to listen to all in one sitting?
No, this was a book that took some time to listen to. I had to take breaks to let things settle in my mind.
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