Carleton Myatt meets Coral Musker, a naïve English chorus girl, aboard the Orient Express as it heads across Europe to Constantinople. As their relationship develops, they find themselves caught up in the fates of the other passengers and drawn into a web of espionage, murder and lies.

Querry, a world famous architect, is the victim of a terrible attack of indifference: he no longer finds meaning in art or pleasure in life. Arriving anonymously at a Congo leper village, he is diagnosed as the mental equivalent of a 'burnt-out case', a leper mutilated by disease and amputation. Querry slowly moves towards a cure, his mind getting clearer as he works for the colony. However, in the heat of the tropics, no relationship with a married woman, will ever be taken as innocent...

Trusted by no one, trusting nobody, the Confidential Agent is sent to England. But before his mission has barely begun, he comes face to face with an agent from the other side. As the car he is driving is run down in the fog, a thought strikes him: "It isn't probable - not in England, but it seems to be true, nonetheless - they're going to kill me."

A leak is traced to a small sub-section of the secret service, sparking off the inevitable security checks, tensions and suspicions. The sort of atmosphere, perhaps, where mistakes could be made? For Maurice Castle, it is the end of the line anyway, and time for him to retire to live peacefully with his wife and child. But no-one escapes so easily from the lonely, isolated, neurotic world of the SIS.

Graham Greene's first published novel tells the story of Andrews, a young man who has betrayed his fellow smugglers and fears their vengeance. Fleeing from them, with no hope of pity or salvation, he takes refuge in the house of a young woman, also alone in the world. Elizabeth persuades him to give evidence against his accomplices in court, but neither she nor Andrews is aware that to both criminals and authority, treachery is as great a crime as smuggling.