
So Very Small
How Humans Discovered the Microcosmos, Defeated Germs–and May Still Lose the War Against Infectious Disease
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Narrated by:
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Mike Cooper
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By:
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Thomas Levenson
About this listen
“An elegant, wide-ranging history” (The New York Review of Books) of the centuries-long quest to discover the critical role of germs in disease that reveals as much about human reasoning—and the pitfalls of ego—as it does about microbes.
“Levenson takes readers through an entertaining . . . journey of missed opportunities in microbiology and the eventual advances that arose in this field.”—Science
Scientists and enthusiastic amateurs first confirmed the existence of living things invisible to the human eye in the late seventeenth century. So why did it take two centuries to connect microbes to disease? As late as the Civil War in the 1860s, most soldiers who perished died not on the battlefield but of infected wounds, typhoid, and other diseases. Twenty years later, the outcome might have been different, following one of the most radical intellectual transformations in history: germ theory, the recognition that the tiniest forms of life have been humankind’s greatest killers. It was a discovery centuries in the making, and it transformed modern life and public health.
As Thomas Levenson reveals in this globe-spanning history, it has everything to do with how we see ourselves. For centuries, people in the West, believing themselves to hold God-given dominion over nature, thought too much of humanity and too little of microbes to believe they could take us down. When nineteenth-century scientists finally made the connection, life-saving methods to control infections and contain outbreaks soon followed. The next big break came with the birth of the antibiotic era in the 1930s. And yet, less than a century later, the promise of the antibiotic revolution is already receding due to years of overuse. Is our self-confidence getting the better of us again?
So Very Small follows the thread of human ingenuity and hubris across centuries—along the way peering into microscopes, spelunking down sewers, visiting army hospitals, traipsing across sheep fields, and more—to show how we came to understand the microbial environment and how little we understand ourselves. Levenson traces how and why ideas are pursued, accepted, or ignored—and hence how human habits of mind can, so often, make it terribly hard to ask the right questions.
©2025 Thomas Levenson (P)2025 Random House AudioListeners also enjoyed...
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Critic reviews
“In So Very Small Levenson provides not only the backstory to resistance to variolation but an elegant, wide-ranging history of the discovery of microorganisms and their relation to disease.”—New York Review of Books
“Levenson takes readers through an entertaining, if frustrating, journey of missed opportunities in microbiology and the eventual advances that arose in this field . . . Levenson concludes that ‘we aren’t smarter than the microcosmos,’ and despite centuries of advances, it is clear that he is correct.”—Science
“[So Very Small] offers a compelling story of how microbes have influenced society, seamlessly intertwined with fascinating historical events, while vividly bringing the characters and scientific discoveries to life.”—Alanna Collen, author of 10% Human
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By: Lizzie Wade
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China's Quest for Military Supremacy
- By: Phillip C. Saunders, Joel Wuthnow
- Narrated by: Steve Marvel
- Length: 9 hrs and 51 mins
- Unabridged
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China's Quest for Military Supremacy provides a broad and accessible exploration of Chinese military power, including relations between the Chinese Communist Party and its army, the strategic worldview of Chinese leaders, military strategy and resourcing, conventional and nuclear modernization, military diplomacy and coercion, preparations for war, and the People's Liberation Army's emerging global role.
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Deep Military Analysis
- By Helen C. on 05-19-25
By: Phillip C. Saunders, and others
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A Little Bit of Land
- By: Jessica Gigot
- Narrated by: Julia Whelan
- Length: 5 hrs and 33 mins
- Unabridged
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From midwifing new lambs to harvesting basil, Jessica Gigot invites the listener into her life on a small farm and the uncommon road that led her there. Fascinated by farming and the burgeoning local food movement, she spent her twenties wandering the Pacific Northwest, interning at small farms and doing graduate work in horticulture, always with an eye towards learning as much as she could about how and why people farm.
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Beautiful writing and narrating
- By km on 06-16-25
By: Jessica Gigot
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Proto
- How One Ancient Language Went Global
- By: Laura Spinney
- Narrated by: Emma Spurgin-Hussey
- Length: 9 hrs and 3 mins
- Unabridged
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Daughter. Duhitár-. Dustr. Dukte. Listen to these English, Sanskrit, Armenian and Lithuanian words, all meaning the same thing, and you hear echoes of one of history’s most unlikely journeys. All four languages—along with hundreds of others, from French and Gaelic, to Persian and Polish—trace their origins to an ancient tongue spoken as the last ice age receded. This language, which we call Proto-Indo-European, was born between Europe and Asia and exploded out of its cradle, fragmenting as it spread east and west.
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Brilliant research and narration
- By Dr. Krishnendu Ray on 05-16-25
By: Laura Spinney
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Turning to Birds
- The Power and Beauty of Noticing
- By: Lili Taylor
- Narrated by: Lili Taylor
- Length: 4 hrs and 16 mins
- Unabridged
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Through a series of beautifully crafted essays, Taylor shares her intimate encounters with the birds that have captured her heart and imagination—from tracking flitting woodpeckers through oak trees to spotting majestic blue jays perched on a Manhattan fire escape; from the exhilaration of witnessing a migratory flock from the top of the Empire State Building to the quiet joy of observing a nest of hatchlings in her own backyard. Through simply paying attention to birds, Lili has been shown a parallel world that is wider and deeper, one of constant change and movement, full of life.
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Bird lovers will rejoice!
- By Fascination with Fear on 05-10-25
By: Lili Taylor
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Newton and the Counterfeiter
- The Unknown Detective Career of the World's Greatest Scientist
- By: Thomas Levenson
- Narrated by: Kevin Pariseau
- Length: 9 hrs and 32 mins
- Unabridged
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In 1695, Isaac Newton already renowned as the greatest mind of his agemade a surprising career change. He left quiet Cambridge, where he had lived for 30 years and made his earth-shattering discoveries, and moved to London to take up the post of Warden of His Majestys Mint. Newton was preceded to the city by a genius of another kind, the budding criminal William Chaloner.
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Terrific Historical Biography
- By Megan on 12-12-09
By: Thomas Levenson
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They Poisoned the World
- Life and Death in the Age of Forever Chemicals
- By: Mariah Blake
- Narrated by: Beth Hicks, Mariah Blake
- Length: 6 hrs and 49 mins
- Unabridged
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In 2014, after losing several friends and relatives to cancer, an unassuming insurance underwriter in Hoosick Falls, New York, began to suspect that the local water supply was polluted. When he tested his tap water, he discovered dangerous levels of forever chemicals. This set off a chain of events that led to 100 million Americans learning their drinking water was tainted. Although the discovery came as a shock to most, the U.S. government and the manufacturers of these toxic chemicals had known about their hazards for decades.
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Excellent!
- By Pam on 06-23-25
By: Mariah Blake
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The Great Betrayal
- The Struggle for Freedom and Democracy in the Middle East
- By: Fawaz A. Gerges
- Narrated by: Keval Shah
- Length: 15 hrs and 42 mins
- Unabridged
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The Middle East is in upheaval: a widening chasm between state and society, the failure of governing elites to address citizens' genuine grievances, massive economic mismanagement—all made worse by repeated interventions by Western powers. Why has political change been so difficult to achieve? In The Great Betrayal, Fawaz Gerges argues that the convergence of political authoritarianism, meddling by the West, and the effects of prolonged regional conflicts have produced political paralysis and economic stagnation.
By: Fawaz A. Gerges
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The Hunt for Vulcan
- …And How Albert Einstein Destroyed a Planet, Discovered Relativity, and Deciphered the Universe
- By: Thomas Levenson
- Narrated by: Kevin Pariseau
- Length: 5 hrs and 49 mins
- Unabridged
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For more than 50 years, the world's top scientists searched for the "missing" planet Vulcan, whose existence was mandated by Isaac Newton's theories of gravity. Countless hours were spent on the hunt for the elusive orb, and some of the era's most skilled astronomers even claimed to have found it. There was just one problem: It was never there.
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This is great stuff!
- By Mark A. Hurt on 11-22-15
By: Thomas Levenson
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The Evolution of Cooperation
- By: Robert Axelrod
- Narrated by: Roger Wayne
- Length: 6 hrs
- Unabridged
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A vital book for leaders and decision makers, The Evolution of Cooperation reveals how cooperative principles help us think better about everything from military strategy, to political elections, to family dynamics.
By: Robert Axelrod
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Strangers in the Land
- Exclusion, Belonging, and the Epic Story of the Chinese in America
- By: Michael Luo
- Narrated by: Eric Yang
- Length: 17 hrs and 20 mins
- Unabridged
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In 1889, while upholding Chinese exclusion, Supreme Court Justice Stephen J. Field characterized them as “strangers in the land.” Only in 1965 did America’s gates swing open to people like Luo’s parents, immigrants from Taiwan. Today there are more than twenty-two million people of Asian descent in the United States and yet the “stranger” label, Luo writes, remains. Drawing on archives from across the country and written with a New Yorker writer’s style and sweep, Strangers in the Land is revelatory and unforgettable, an essential American story.
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Thank you for this important history
- By cindy on 06-22-25
By: Michael Luo
Very written and very well performed.
A gripping account of a triumph of humanity, and our limitations
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Great read!
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Loved the historical perspective of so very
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