
Pandora’s Lab
Seven Stories of Science Gone Wrong
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Narrated by:
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Greg Tremblay
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By:
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Paul A. Offit MD
About this listen
What happens when ideas presented as science lead us in the wrong direction? History is filled with brilliant ideas that gave rise to disaster, and this book explores the most fascinating - and significant - missteps.
Pandora's Lab takes us from opium's heyday as the pain reliever of choice to recognition of opioids as a major cause of death in the United States; from the rise of trans fats as the golden ingredient for tastier, cheaper food to the heart disease epidemic that followed; and from the cries to ban DDT for the sake of the environment to an epidemic-level rise in world malaria.
These are today's sins of science - as deplorable as mistaken ideas from the past such as advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, explained by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using as case studies some of today's most controversial creations: e-cigarettes, GMOs, and drug treatments for ADHD.
For every "Aha!" moment that should have been an "Oh no", this book is an engrossing account of how science has been misused disastrously - and how we can learn to use its power for good.
©2017 Paul A. Offit (P)2017 Blackstone Audio, Inc.Listeners also enjoyed...
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The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.
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very detailed, but very statistical
- By ekhensel15 on 01-12-19
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Knowing What We Know
- The Transmission of Knowledge: From Ancient Wisdom to Modern Magic
- By: Simon Winchester
- Narrated by: Simon Winchester
- Length: 14 hrs and 19 mins
- Unabridged
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From the creation of the first encyclopedia to Wikipedia, from ancient museums to modern kindergarten classes—this is Simon Winchester’s brilliant and all-encompassing look at how humans acquire, retain, and pass on information and data, and how technology continues to change our lives and our minds. Throughout this fascinating tour, Winchester forces us to ponder what rational humans are becoming. What good is all this knowledge if it leads to lack of thought? What is information without wisdom?
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Colorful anecdotes but tiring after a while.
- By Thumb Guy on 05-03-23
By: Simon Winchester
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The Disappearing Spoon
- And Other True Tales of Madness, Love, and the History of the World from the Periodic Table of the Elements
- By: Sam Kean
- Narrated by: Sean Runnette
- Length: 12 hrs and 34 mins
- Unabridged
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Reporter Sam Kean reveals the periodic table as it’s never been seen before. Not only is it one of man's crowning scientific achievements, it's also a treasure trove of stories of passion, adventure, betrayal, and obsession. The infectious tales and astounding details in The Disappearing Spoon follow carbon, neon, silicon, and gold as they play out their parts in human history, finance, mythology, war, the arts, poison, and the lives of the (frequently) mad scientists who discovered them.
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Great Book, Great Narration, But...
- By Henny Button on 09-18-10
By: Sam Kean
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Quackery
- A Brief History of the Worst Ways to Cure Everything
- By: Lydia Kang, Nate Pedersen
- Narrated by: Hillary Huber
- Length: 10 hrs and 29 mins
- Unabridged
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What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.
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Computer-generated Narrator. Dated Humour.
- By Nemo on 12-28-18
By: Lydia Kang, and others
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The Age of Wonder
- How the Romantic Generation Discovered the Beauty and Terror of Science
- By: Richard Holmes
- Narrated by: Gildart Jackson
- Length: 21 hrs and 26 mins
- Unabridged
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When young Joseph Banks stepped onto a Tahitian beach in 1769, he hoped to discover Paradise. Inspired by the scientific ferment sweeping through Britain, the botanist had sailed with Captain Cook in search of new worlds. Other voyages of discovery—astronomical, chemical, poetical, philosophical—swiftly follow in Richard Holmes's thrilling evocation of the second scientific revolution.
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Misleading title
- By Diane on 08-04-11
By: Richard Holmes
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Patient Zero
- A Curious History of the World's Worst Diseases
- By: Lydia Kang MD, Nate Pedersen
- Narrated by: Hillary Huber
- Length: 14 hrs and 17 mins
- Unabridged
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From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.
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Can’t listen to the reader
- By Doug Clyde on 07-21-22
By: Lydia Kang MD, and others
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Who We Are and How We Got Here
- By: David Reich
- Narrated by: John Lescault
- Length: 10 hrs and 50 mins
- Unabridged
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Geneticists like David Reich have made astounding advances in the field of genomics, which is proving to be as important as archaeology, linguistics, and written records as a means to understand our ancestry. In Who We Are and How We Got Here, Reich allows listeners to discover how the human genome provides not only all the information a human embryo needs to develop but also the hidden story of our species.
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Great Book, No Maps Available thru Audible
- By Jane W. on 07-15-18
By: David Reich
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Stuff Matters
- Exploring the Marvelous Materials That Shape Our Man-Made World
- By: Mark Miodownik
- Narrated by: Matthew Waterson
- Length: 6 hrs and 22 mins
- Unabridged
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In Stuff Matters, Miodownik entertainingly examines the materials he encounters in a typical morning, from the steel in his razor and the graphite in his pencil to the foam in his sneakers and the concrete in a nearby skyscraper. He offers a compendium of the most astounding histories and marvelous scientific breakthroughs in the material world.
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Might be a good pick for a young teen
- By Ross on 03-26-25
By: Mark Miodownik
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I Contain Multitudes
- The Microbes Within Us and a Grander View of Life
- By: Ed Yong
- Narrated by: Charlie Anson
- Length: 9 hrs and 52 mins
- Unabridged
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Joining the ranks of popular science classics like The Botany of Desire and The Selfish Gene, a groundbreaking, wondrously informative, and vastly entertaining examination of the most significant revolution in biology since Darwin - a "microbe's-eye view" of the world that reveals a marvelous, radically reconceived picture of life on Earth.
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Undoes what you've learned from the headlines
- By Tristan on 10-14-16
By: Ed Yong
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A Brief History of Everyone Who Ever Lived
- The Human Story Retold Through Our Genes
- By: Adam Rutherford
- Narrated by: Adam Rutherford
- Length: 12 hrs and 13 mins
- Unabridged
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In our unique genomes, every one of us carries the story of our species - births, deaths, disease, war, famine, migration, and a lot of sex. But those stories have always been locked away - until now. Who are our ancestors? Where did they come from? Geneticists have suddenly become historians, and the hard evidence in our DNA has completely upended what we thought we knew about ourselves. Acclaimed science writer Adam Rutherford explains exactly how genomics is completely rewriting the human story - from 100,000 years ago to the present.
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I wish this book was in American high schools.
- By melody sheldon on 03-31-19
By: Adam Rutherford
What listeners say about Pandora’s Lab
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- E. A. Newton
- 05-27-19
Very very interesting, and challenges you to think for yourself
I am one of the most curious people I know - curious and a bit of a skeptic because so much information is skewed by perspective. But, Dr. Offit gives you the tools to come to your own conclusions. He doesn’t just give you information, but tells you how to discern between what’s a current media fad, what’s really going on, and what to be cautious about.
My only criticism is: during the chapter about nitrogen, Dr. Offit doesn’t mention that, while the phenomenon he discusses was a key element, it was Mao’s attempted Great Leap Forward that led to the atrocities that occurred there. A fantastic book about this time in recent history is The Fall and Rise of China.
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- Fed Barona
- 06-03-19
Great format and approach that loses its way
It did start out much like a James Burch "Connections" show which I REALLY liked. These first few chapters followed this script and made my experience comfortable and I couldn't help but anticipate the next facts coming around the corner.
Unfortunately, the author decided to take the scientific facts, which were the stars of his show, and have them take a back seat to his political stance and I had to suffer opinion and a stray from the scientific path he had so well planned for the previous chapters. After that detour, although I was still just as drawn in by the story he presented, we never quite got back on that original "path" of describing a seemingly benign discovery and how it ultimately led to a horrific or tragic outcome. I think those items were still presented, just not as elegantly.
This is still a fantastic book and I thoroughly enjoyed the facts and story that surrounded the history. I learned a lot. Regardless of your political slant, I believe you'll find his addition of a political charge as a distraction and a bit indulgent.
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- Anonymous User
- 09-14-20
Very good narrator
Nice book informative concerning the latest problems of our era and the dangers that exist due to bad science.
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- Anonymous User
- 09-22-20
Disturbing
It goes to show we aren't as smart, as a species, as we like to think we are. Today's miracle cure is tomorrow's quack cure or even killer.
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- Travis Baublitz
- 06-20-19
Amazing!
A very informative and enlightening listen. It truly opened my eyes to many things I took for truth
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- Aizat Mazlan
- 07-27-21
An absolute gem.
Lovely reading. Full of interesting and credible stories. The narrator is great and clear.
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- Jon Harwood
- 03-22-22
Timely: Use, misuse, and abuse of science.
Some very important lessons from high profile episodes in science. Although I don't quite believe every word of it, that's kind of the point.
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- Andrew
- 04-03-22
Thinking Book
Think before you judge and maybe don't make your judgement final. That's what I would call the underlying theme. That and data should impact your judgement more often than feelings. It's got great examples of when science became no longer science and how it effects society.
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- Jennifer
- 01-01-22
Interesting and thought provoking
I really enjoyed the narrative style that explained the invention followed by the unintended consequences.
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- Anonymous User
- 07-17-22
Essential reading
This book is essential reading/listening for anyone interested in health and wellness. There is so much misinformation out there, and this book is an excellent review of critical thinking and scientific method in determining what is beneficial and what is pseudoscience.
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