
Never Enough
The Neuroscience and Experience of Addiction
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Narrated by:
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Judith Grisel
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By:
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Judith Grisel
About this listen
A New York Times Best Seller
From a renowned behavioral neuroscientist and recovering addict, a rare pause-resisting work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction.
Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after 25 years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey.
In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice.
With more than one in five people over the age of 14 addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities.
Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.
©2019 Judith Grisel (P)2019 Random House AudioListeners also enjoyed...
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Critic reviews
“Dr. Judith Grisel, a neuroscientist and a person in long term addiction recovery, juxtaposes stark examples from her own tortured past, methodically connecting each experience to the hard science of addiction neurobiology. Doing this captures our attention as we peer into one of the most complex puzzles of humankind. The science behind addiction comes alive in its sorrow and grandeur. When you pick up this book get ready for an intense ride.” (Paul H. Earley, MD, DFASAM; president-elect, American Society of Addiction Medicine)
“Grisel is a recovering addict, a neuroscientist, and a talented writer. Who better to help us understand drug addiction? This book is as informative as it is moving. Here you will find clearly explained science and a gripping account of the personal and societal toll of drug addiction.” (Martha J. Farah, PhD, director, Center for Neuroscience & Society, and Walter H. Annenberg professor in the natural sciences, University of Pennsylvania)
“It is rare to have a book on addiction marry emotional and scientific views. Never Enough sends a message of hope in relaying Judith Grisel’s pathway out of her own drug quagmire - notably, one triggered by the positive and compassionate responses of those near and dear to her.” (Christopher J. Evans, PhD, director, Hatos Center for Neuropharmacology, UCLA)
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- A Cure for Compulsive Shopping and Spending to Free Yourself from Addiction!
- By: Jeffrey Powell
- Narrated by: Millian Quinteros
- Length: 58 mins
- Unabridged
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Shopping is a raging phenomenon among developed countries and has been studied over and over. Sociologists say it's a female drive in an attempt to explain the differences in shopping behavior between men and women. It was said that the same obsession of men over sports can be linked to the way women go crazy on Black Friday sales or on mall openings.
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Offensive and sexist
- By mcw on 12-17-15
By: Jeffrey Powell
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The 30-Day Money Cleanse
- Take Control of Your Finances, Manage Your Spending, and De-Stress Your Money for Good
- By: Ashley Feinstein Gerstley
- Narrated by: Teri Schnaubelt
- Length: 2 hrs and 59 mins
- Unabridged
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Like food, money is something all of us use but none of us talk about - creating a stressful relationship that most of us suffer from, obsess over, and try to avoid altogether because it feels too impossible to manage. No matter your income, understanding and controlling your own financial position will allow you to not just exist securely, but to be happy and free in your choices.
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TOO WHIMSICAL
- By Courtney Kimbrough on 12-21-19
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Addiction, Procrastination, and Laziness
- A Proactive Guide to the Psychology of Motivation
- By: Roman Gelperin
- Narrated by: Paul Brion
- Length: 4 hrs and 3 mins
- Unabridged
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What is motivation? Why do we feel totally paralyzed to do certain things, and utterly unable to quit others? Too many people conclude, falsely, that they are just lazy or lacking in willpower. But what they lack is a correct understanding of their own minds, of motivation, and the way that it operates.
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If you saw this on Instagram ads you’re as gullible as I was
- By max on 10-30-19
By: Roman Gelperin
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The Nocturnal Brain
- Nightmares, Neuroscience, and the Secret World of Sleep
- By: Guy Leschziner
- Narrated by: Guy Leschziner
- Length: 9 hrs and 53 mins
- Unabridged
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With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.
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Not Suitable as an audio book.
- By Alchemist585 on 09-05-19
By: Guy Leschziner
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Undoing Drugs
- The Untold Story of Harm Reduction and the Future of Addiction
- By: Maia Szalavitz
- Narrated by: Samantha Desz
- Length: 14 hrs and 3 mins
- Unabridged
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From “one of the bravest, smartest writers about addiction anywhere” (Johann Hari, New York Times best-selling author) - the untold story of harm reduction, a surprisingly simple idea with enormous power.
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Wow! An amazing amount of harm reduction info!
- By Bobbi Jensen, Criminal Justice Consultant, Educator and Reform Activist on 09-19-21
By: Maia Szalavitz
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Understanding Addiction
- Know Science, No Stigma
- By: Dr. Charles Smith, Dr. Jason Hunt
- Narrated by: Scott R. Pollak
- Length: 2 hrs and 45 mins
- Unabridged
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Doctors Chuck Smith and Jason Hunt bring a unique and important perspective to the subject of addiction. Experts in the field, Smith and Hunt have personal, firsthand experience with the humiliation and shame that accompanies substance use disorder. But addiction, as they point out, is a disease, no less so than diabetes or heart disease, and it needs to be treated as such. If you, or a loved one, is struggling with addiction, you'll find help in Smith and Hunt's book. When one understands the science behind addiction, one can begin to move forward. Beyond the stigma lies hope.
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Uncommon Sense
- By spring on 06-20-25
By: Dr. Charles Smith, and others
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The Biology of Desire
- Why Addiction Is Not a Disease
- By: Marc Lewis PhD
- Narrated by: Don Hagen
- Length: 7 hrs and 40 mins
- Unabridged
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The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease based on evidence that brains change with drug use. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it's supposed to do - seek pleasure and relief - in a world that's not cooperating.
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An important addition to understanding addiction.
- By Jeff M on 02-28-16
By: Marc Lewis PhD
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Successful Aging
- A Neuroscientist Explores the Power and Potential of Our Lives
- By: Daniel J. Levitin
- Narrated by: Daniel J. Levitin
- Length: 18 hrs and 37 mins
- Unabridged
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Levitin looks at the science behind what we all can learn from those who age joyously, as well as how to adapt our culture to take full advantage of older people's wisdom and experience. Throughout his exploration of what aging really means, using research from developmental neuroscience and the psychology of individual differences, Levitin reveals resilience strategies and practical, cognitive enhancing tricks everyone should do as they age.
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Prejudiced and snooty
- By Mother of Chickens on 01-30-20
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Dopamine Nation
- Finding Balance in the Age of Indulgence
- By: Dr. Anna Lembke
- Narrated by: Dr. Anna Lembke
- Length: 6 hrs and 11 mins
- Unabridged
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This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting....
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Interesting but feels incomplete
- By Chris on 09-02-21
By: Dr. Anna Lembke
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The Addictive Personality
- Understanding the Addictive Process and Compulsive Behavior, Second Edition
- By: Craig Nakken
- Narrated by: Fred Sanders
- Length: 4 hrs and 12 mins
- Unabridged
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For over two decades, The Addictive Personality has helped people understand the process of addiction. Now, through this second edition, author Craig Nakken brings new depth and dimension to our understanding of how an individual becomes an addict. Going beyond the definition that limits dependency to the realm of alcohol and other drugs, Nakken uncovers the common denominator of all addiction and describes how the process is progressive.
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Excellent book!
- By Amazon Customer on 10-24-19
By: Craig Nakken
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Overcome
- A Memoir of Abuse, Addiction, Sex Work, and Recovery
- By: Amber van de Bunt
- Narrated by: Amber van de Bunt
- Length: 6 hrs and 47 mins
- Unabridged
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From an early age, Amber van de Bunt knew she wasn't like the other girls in town. From childhood struggles with depression and eating disorders, her years as a topless dancer in Florida, and an eventual abortion and suicide attempt, to her rebirth in Los Angeles as a porn star named Karmen Karma, overcoming her relationship with her abusive mother, and her struggle to maintain a clean and sober lifestyle - van de Bunt's life has been a roller coaster. With humor, alacrity, and profound insight, she reveals her deepest, darkest secrets and pulls no punches - least of all with herself.
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Talk about Owning and Living for YOURSELF
- By LuLuababa2 on 07-19-19
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In the Realm of Hungry Ghosts
- Close Encounters with Addiction
- By: Gabor Maté MD
- Narrated by: Daniel Maté
- Length: 16 hrs and 26 mins
- Unabridged
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In this timely and profoundly original book, best-selling writer and physician Gabor Maté looks at the epidemic of addictions in our society, tells us why we are so prone to them, and what is needed to liberate ourselves from their hold on our emotions and behaviours.
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Gabor should have been the narrator
- By Stacey on 08-16-19
By: Gabor Maté MD
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We Are the Luckiest
- The Surprising Magic of a Sober Life
- By: Laura McKowen
- Narrated by: Laura McKowen
- Length: 7 hrs
- Unabridged
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What could possibly be “lucky” about addiction? Absolutely nothing, thought Laura McKowen when drinking brought her to her knees. As she puts it, she “kicked and screamed . . . wishing for something - anything - else” to be her issue. The people who got to drink normally, she thought, were so damn lucky. But in the midst of early sobriety, when no longer able to anesthetize her pain and anxiety, she realized that she was actually the lucky one. Lucky to feel her feelings, live honestly, really be with her daughter, change her legacy.
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Influencer Recovery, Part One
- By Keith Keller on 01-31-20
By: Laura McKowen
My only critique is that her voice is soft and slow, making the content feel uninteresting at times. Also, the text is very heavy and complicated. I would highly reccomend the Kindle or paper version so one can really examine the text.
An important read, just not on Audible
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She frames the problem in stark terms: a) 16% of Americans over the age of twelve have an addiction problem b) a quarter of deaths are attributable to drugs c) drug treatment consumes a tenth of all healthcare spending (or twice as much as what we spend on cancer) d) there has been little improvement in treatment e) and only 10% of intervention is successful.
The main culprits that lead to the disease are having a genetic predisposition, exposure (and even worse from puberty to adulthood), and a catalyzing environment. The genetic component is interesting as she uses the example that Asians who get flush are less likely to be alcoholics and smokers who tend to absorb more nicotine smoke less.
Grisel explores different classes of drugs and what you find is the common thread that there is no gain without a later, equal loss. As far back as Socrates, this interplay of pleasure and pain has been well known. For each high, you pay it back with low or as the Grateful Dead put it, "Too much is never enough."
She imparts such interesting facts such as:
- Valium in the 1970's was used by one in five women and sent more people to the hospital than all other illicit drugs
- The doctors who discovered barbiturates died of overdoses themselves
- In 2010, the of alcohol (in poor health, drunk driving, crime) was 249 billion
- Kat production uses up 40% of Yemen's water supply
- Since ecstasy, unlike cocaine, effects transporters and not receptors, addicts are never the same regardless of how long they have been clean
Paraphrasing Grisel in her summation of the range of drugs: Alcohol and downers are negatively reinforcing because they reduce anxiety, Opiates reduce suffering, Stimulants reduce boredom. People tend to abuse those drugs that compliment themselves (such as the anxious who prefer alcohol) but also someone who is nervous who drinks to self medicate will become nervous.
I wish there was an optimistic conclusion but by the end of reading this I was worried that my own daily coffee habit had impaired my natural ability to awaken. Dependence is hard to overcome. Grisel recounts the story of her sharing a crack pipe with a toothless, homeless person who was deluded into thinking he was on top of the world. Ultimately, it was not jail or seeing her friends dying but rather her reconnection with her father that led to her recovery. She herself advises decreasing the drug's dosage, supplying palliative medicine for the inevitable withdrawal, and creating a support network. She points out that addicts naturally posses what are typically beneficial traits, like being heterodox, strong-willed and persistent. These traits certainly are apparent in this excellent scientist's work.
A Great Work on Addiction
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Up-to-date and informative
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Good and informative
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Given me additional insight, and has helped me become even more compassionate. The personal revelations are bravely bared. Very impressive.
Loved it!
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Strongly recommend it
Great balance!
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Certainty
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homerun
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Great research into an uncomfortable topic
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Objectively researched and presented but put in a personal perspective that was effective. I liked it and want to listen to it again to ponder it some more. The ending conclusions clarified and elaborated on how I tend to view addiction.
A professional narrator may have been a better choice for audio version or some coaching on making it less low energy voice.
Very worthwhile and comprehensive book, from chocolate to heroin
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