Vienna, 1938. Samuel Adler is five years old when his father disappears during Kristallnacht—the night his family loses everything. As her child’s safety becomes ever harder to guarantee, Samuel’s mother secures a spot for him on a Kindertransport train out of Nazi-occupied Austria to England. He boards alone, carrying nothing but a change of clothes and his violin.

Violeta comes into the world on a stormy day in 1920, the first girl in a family with five boisterous sons. From the start, her life is marked by extraordinary events, for the ripples of the Great War are still being felt, even as the Spanish flu arrives on the shores of her South American homeland almost at the moment of her birth.

The House of the Spirits brings to life the triumphs and tragedies of three generations of the Trueba family. The patriarch Esteban is a volatile, proud man whose voracious pursuit of political power is tempered only by his love for his delicate wife, Clara, a woman with a mystical connection to the spirit world. When their daughter, Blanca, embarks on a forbidden love affair in defiance of her implacable father, the result is an unexpected gift to Esteban.

In 1939, as Poland falls under the shadow of the Nazis, young Alma Belasco's parents send her away to live in safety with an aunt and uncle in their opulent mansion in San Francisco. There, as the rest of the world goes to war, she encounters Ichimei Fukuda, the quiet and gentle son of the family's Japanese gardener. Unnoticed by those around them, a tender love affair begins to blossom. Following the Japanese attack on Pearl Harbor, the two are cruelly pulled apart.

Orphaned at birth, Eliza Sommers is raised in the British colony of Valparaíso, Chile, by the well-intentioned Victorian spinster Miss Rose and her more rigid brother Jeremy. Just as she meets and falls in love with the wildly inappropriate Joaquín Andieta, a lowly clerk who works for Jeremy, gold is discovered in the hills of northern California. By 1849, Chileans of every stripe have fallen prey to feverish dreams of wealth. Joaquín takes off for San Francisco to seek his fortune, and Eliza, pregnant with his child, decides to follow him.

Born in the Hispanic barrio of Los Angeles, Gregory Reeves grew up in poverty, survived the killing fields of Vietnam, and is now a lawyer in San Francisco. Though he has successfully survived this hard journey, Gregory’s life has suddenly gone off the rails thanks to an illusory and wrongheaded quest that has left him feeling lost and listless. To find what he is missing and what his heart truly wants, he must return to his roots. Only by excavating the past can he see the way to his future.

During the biggest Brooklyn snowstorm in living memory, Richard Bowmaster, a lonely university professor in his 60s, hits the car of Evelyn Ortega, a young undocumented immigrant from Guatemala, and what at first seems an inconvenience takes a more serious turn when Evelyn comes to his house, seeking help. At a loss, the professor asks his tenant, Lucia Maraz, a fellow academic from Chile, for her advice.

Eva Luna is the daughter of a professor’s assistant and a snakebitten gardener - born poor, orphaned at an early age, and working as a servant. Eva is a naturally gifted and imaginative storyteller who meets people from all stations and walks of life. Though she has no wealth, she trades her stories like currency with people who are kind to her.

Born a slave on the island of Saint-Domingue, Zarit - known as Tt - is the daughter of an African mother she never knew and one of the white sailors who brought her into bondage. Though her childhood is one of brutality and fear, Tt finds solace in the traditional rhythms of African drums and in the voodoo loas she discovers through her fellow slaves.

The Jackson women, Indiana and Amanda, have always had each other. Though their bond is strong, mother and daughter are as different as night and day. Indiana, a beautiful holistic healer, is a free-spirited bohemian. Long divorced from Amanda's father, she's reluctant to settle down with either of the men who want her - Alan, the wealthy scion of one of San Francisco's elite families, and Ryan, an enigmatic, scarred former Navy SEAL. While her mom looks for the good in people, Amanda is fascinated by the dark side of human nature - as is her father, the SFPD's deputy chief of homicide.

Fifteen-year-old Alexander Cold has the chance to take the trip of a lifetime. Parting from his family and ill mother, Alexander joins his fearless grandmother, a magazine reporter for International Geographic, on an expedition to the dangerous, remote world of the Amazon. Their mission, along with the others on their team - including a celebrated anthropologist, a local guide and his young daughter Nadia, and a doctor - is to document the legendary Yeti of the Amazon known as the Beast.

In the late 1930s, civil war grips Spain. When General Franco and his Fascists succeed in overthrowing the government, hundreds of thousands are forced to flee in a treacherous journey over the mountains to the French border. Among them is Roser, a pregnant young widow, who finds her life intertwined with that of Victor Dalmau, an army doctor and the brother of her deceased love. In order to survive, the two must unite in a marriage neither of them desires.

“When I say that I was a feminist in kindergarten, I am not exaggerating,” begins Isabel Allende. As a child, she watched her mother, abandoned by her husband, provide for her three small children without “resources or voice.” Isabel became a fierce and defiant little girl, determined to fight for the life her mother couldn’t have.

Though she was born into poverty, Inés Suárez, a seamstress in 16th-century Spain, embodies the same restless hope and opportunism that fuels her nation’s conquest of the Americas. Learning that her shiftless husband has vanished, Inés uses his disappearance to embark on her own adventure. It is a journey will lead her to Pedro de Valdivia - a conquistador who becomes the first royal governor of Chile - and to a love that not only changes her life but the course of history.

Irene Beltrán is a force to be reckoned with. As a magazine journalist, an unusual profession for a woman with her privileged upbringing, she is constantly challenging the oppressive regime. Her investigative partner is photographer Francisco Leal, the son of impoverished Spanish Marxist émigrés. Together, they are an inseparable team and - despite Irene’s engagement to an army captain - form a passionate connection.