Aristotle is an angry teen with a brother in prison. Dante is a know-it-all who has an unusual way of looking at the world. When the two meet at the swimming pool, they seem to have nothing in common. But as the loners start spending time together, they discover that they share a special friendship - the kind that changes lives and lasts a lifetime. And it is through this friendship that Ari and Dante will learn the most important truths about themselves and the kind of people they want to be.

During his years in a neural-health facility, Pat Peoples has formulated a theory about silver linings. He believes that his life is a movie produced by God, that his mission is to become physically fit and emotionally supportive, and that if he succeeds, his happy ending will be the return of his estranged wife, Nikki. When Pat goes to live with his parents, everything seems changed: no one will talk to him about Nikki, and his new therapist seems to be recommending adultery as a form of therapy.

The stories in This Is How You Lose Her, by turns hilarious and devastating, raucous and tender, lay bare the infinite longing and inevitable weaknesses of our all-too-human hearts. They capture the heat of new passion, the recklessness with which we betray what we most treasure, and the torture we go through - "the begging, the crawling over glass, the crying" - to try to mend what we've broken beyond repair. They recall the echoes that intimacy leaves behind, even where we thought we did not care.

After 27 years of marriage and three children, Anna Oh - wife, mother, outsider artist - has fallen in love with Viveca, the wealthy Manhattan art dealer who orchestrated her success. They plan to wed in the Oh family’s hometown of Three Rivers in Connecticut. But the wedding provokes some very mixed reactions and opens a Pandora’s Box of toxic secrets - dark and painful truths that have festered below the surface of the Ohs' lives.

On a beautiful fall evening, in the middle of a game of hide-and-seek, five-year-old Bobby Clark is kidnapped by his estranged father, a shiftless man with a history of domestic violence and drug abuse. Bobby's twin brother Ricky watches, terrified, from his hiding place behind the bougainvillea, while mother Tabby, who also struggles with addiction, lies inebriated on the living room floor.

Ed Kennedy is an underage cabdriver without much of a future. He's pathetic at playing cards, hopelessly in love with his best friend, Audrey, and utterly devoted to his coffee-drinking dog, the Doorman. His life is one of peaceful routine and incompetence, until he inadvertently stops a bank robbery.

Ruth and her little brother, Aubrey, are just teenagers when their older brother ships off to Iraq. When Joseph returns, uninjured, only three and a half months later, Ruth is happy he is safe but also deeply worried. How can it be that her courageous big brother has been dishonorably discharged for refusing to go out on duty? Aubrey can't believe that his hero doesn't have very good reasons.

What's it like to be undocumented? High school senior M.T. knows all too well. With graduation and an uncertain future looming, she must figure out how to grow up in the only country she's ever called home... a country in which she's "illegal". M.T. was born in Argentina and brought to America as a baby without any official papers. And as questions of college, work, and the future arise, M.T. will have to decide what exactly she wants for herself, knowing someone she loves will unavoidably pay the price for it.

With all his family and friends gone except an estranged grandson, retired Major League ballplayer Murray McBride is looking for a reason to live. He finds it in Jason Cashman, a spirited 10-year-old boy with a terminal heart defect and a list of five things he wants to do before he dies. Murray is determined to help Jason fulfill his dreams. Together, they race against the limited time each has left, ticking off Jason's wishes one by one.

Valerie Wilson Wesley's crime-fighting heroine Tamara Hayle is loved by fans for her sleuthing abilities and her sardonic wit. Juggling several crises at once, Tamara really has her hands full after her young son witnesses a brutal murder.

For five years Pearl has managed to keep the past from catching up to her and her bright, frail five-year-old son. Life has given her every reason to mistrust people, but circumstances force her to trust her neighbor Mitch with watching Leonard while she goes off to work. Then one day Pearl drops her son off, and never returns.

Michael Steeb is an aimless 21-year-old pot farmer in Central California in the 1980s. He has no real plans or interests...until the day he connects with memories of a life that seems to belong to someone else. That "spirit" is Walter, a young American soldier killed in World War II. Michael's task is the near-impossible: to lead Walter's family to closure and peace, to deliver the real truth behind Walter's Purple Heart, and to somehow achieve the forgiveness absent for so many years so Walter can move on.

When their hard-drinking but loving father dies in a car accident, teenage brothers Kyle and Klint Hayes face a bleak prospect: leaving their Pennsylvania hometown for an uncertain life in Arizona with the mother who ran out on them years ago. But in a strange twist of fate, their town's matriarch, an eccentric, wealthy old woman whose family once owned the county coal mines, hears the boys' story and takes them in.

Lies from the past and a dangerous present collide when, after fifteen years in exile, Michelle Miller returns to her tiny hometown of Lorida, Florida. With her mother in the hospital, she’s forced to reckon with the broken relationships she left behind: with her family, with friends, and with herself.

In the predawn hours, a woman's marriage crumbles with a single confession. Across town, an immigrant family struggles to fit in and get by in the land of opportunity. Three thousand miles away, a soldier wakes up in Walter Reed hospital with the vague feeling that he’s done something awful. In a single moment, these disparate lives intersect. Faced with seemingly insurmountable loss, each person must decide whether to give in to despair, or to find the courage and resilience to rise.