After nearly a decade as a professional drummer, Diana Petrell leaves her rock-star life behind to continue her residency in emergency medicine. She's determined not to let anything stop her - not even falling in love with her aloof mentor, Dr. Emily Barnes. Emily has only ever focused on her career as a senior attending in the emergency department, and she isn't happy about having to babysit a resident with a 10-year gap in her resume, no matter how intriguing she is. But every time they work together, it's not just their patients' heartbeat that gets a little irregular.

Dr. Galen Burgess has a reputation for keeping it casual. She likes women close - but not too close. Nothing is more important to her than her budding surgical career as chief surgical resident at Boston City Hospital. After spending years trying, and failing, to please her father, Galen knows getting close enough to care is a recipe for heartbreak. Everything in her carefully structured life begins to change when she meets her newest intern, the disconcertingly beautiful Dr. Rowan Duncan.

Nearly 26 years after receiving her first heart transplant, Amy Silverstein's donor heart plummeted into failure. If she wanted to live, she had to take on the grueling quest for a new heart - immediately. A shot at survival meant uprooting her life and moving across the country to California. When her friends heard of her plans, there was only one reaction: "I'm there." Nine remarkable women - Joy, Jill, Leja, Jody, Lauren, Robin, Valerie, Ann, and Jane - put demanding jobs and pressing family obligations on hold to fly across the country and be by Amy's side.

I’ve sworn off men to focus on my dream job that starts on Monday. But my best friend talks me into a final night of fun—a blind date. I only agree because the guy is going to work as a doctor in Africa. It’s the best date of my life. Dr. Africa makes me laugh and swoon, and I want to give him a thorough physical examination. He turns into Dr. One Night Stand, and I’m not sad about it. Monday morning, I’m enthusiastic and excited, until I bump into...you guessed it.

Fresh out of medical school, Linda D. Dahl was nervous to begin her surgical residency in the Bronx. Compounding the long hours and overwhelming workload, Dahl felt like a perpetual fish out of water. One night, at her husband’s urging, Dahl watched a boxing match between Shane Mosley and Oscar De La Hoya. Watching Mosley survive against the odds gave Dahl hope that she, too, could find her footing. Later, when she was in practice on the Upper East Side, Dahl received a phone call from the New York State Athletic Commission. They were looking for a fight doctor. Dahl accepted.

Ren Dunbar is used to never fitting in—anywhere. Graduating high school at 13 and med school at 19 pretty much guaranteed she’d always have trouble proving she belonged, but she’s okay with that. She prefers the solitude of the lab over the raucous atmosphere in the OR, which would be fine except she’s a surgery resident. Winning the Benjamin Franklin Prize in surgery is just the proof she needs to show everyone she deserves to be part of their world.

Pregnant and disgraced, soap opera star Laura Munro's life is in shambles. After 10 years of working her butt off in TV and movies, a rage-filled incident with an intrusive paparazzo threatens not only her career, but her dreams of becoming a documentary filmmaker. Hoping people will forget, Laura takes leave from her soap opera role and escapes to the small Catskill Mountain town of Love Falls. The public needs a break from her, and she needs a safe place to have her baby. She just didn't expect that "safe place" to be on the side of a deserted mountain road.

Lucas Thatcher has always been my enemy. It's been a decade since I've seen him, but our years on opposite coasts were less of a lasting peace and more of a temporary cease-fire. Now that we're both back in our small town, I know Lucas expects the same old war, but I've changed since high school - and from the looks of it, so has he. The arrogant boy who was my teenage rival is now a chiseled doctor armed with intimidating good looks.

Life works in mysterious ways. Four years ago, I became known as the girl with cancer. I refuse to cry. And I refuse to give in. A relationship with a man is the last thing I'm looking for right now, but one night with Parker changes everything. He is persistent, and he knows what he wants. He doesn't treat me like I'm fragile. But he doesn't know, and I'm not ready to tell him.

Westley Worthington has it all. Piles of money, good looks, a head for business, and a seemingly limitless supply of women who want to please him. And that's just the way he likes it. Until a brush with death causes him to rethink his priorities and consider someone besides himself for the first time in his privileged life. Cordelia Cross has never had it easy. Her duty to her family has her working as an assistant to a man she hates just to pay her sister's medical bills.

Taylor Andrews is at the top of her career. Everything she touches turns to gold and the studios know it. Just when she's on track for total television domination, Isabel Chase arrives in her office and slowly turns her world upside down. Isabel is intelligent, sarcastic, and dammit, downright beautiful. Unfortunately, she's the one person that can take away all Taylor has worked for. Will Isabel's success lead to Taylor's downfall? Or perhaps Isabel is all she needs....

Newly promoted police captain Bennett Carlyle considers being project manager for the new district substation the way to prove her worth in the male-dominated upper ranks of the department. But when the first girl she loved returns as the architect with little understanding of the operational needs of a police station, Bennett's career and her heart could face permanent damage. Architect Kerstin Anthony believes the new police substation will be the springboard to her own firm. When she confronts the girl she kissed in high school, now a tantalizing police officer with unrealistic expectations about the new facility, Kerstin's path to success becomes littered with unexpected hurdles.

Anastasia Mikhelson is the rising star of the New York City Ballet. She's sacrificed creature comforts, a social life, as well as her own physical well-being for perfection in dance. Even her reputation as the Ice Queen doesn't faze her. Though Ana's at the peak of her career, competition from a new and noteworthy dancer puts all she's worked for in jeopardy.

Dr. Hong-Wei Wu has come to Copper Point, Wisconsin, after the pressures of a high-powered residency burned him out of his career before he started. Ashamed of letting his family down after all they’ve done for him, he plans to live a quiet life as a simple surgeon in this tiny Northern town. His plans, however, don’t include his outgoing, kind, and attractive surgical nurse, Simon Lane.

For Dr. Brant Layton, the world is meant to be as beautiful as he can sculpt it. He sees a woman’s body as a canvas upon which to work his art. But a wild, crazy, not-to-be-remembered night changes everything. He lands drunk on a plane for Belize, signed on for three-week stint with Doctors International which lands him right in the lap of Dr. Melissa Bell. Melissa is in charge of a small clinic in the jungle which primarily cares for women suffering from abuse. Dr. Bell was hoping for a real doctor, not a raw recruit.