Cassie Salazar and Luke Morrow couldn't be more different. Sharp-witted Cassie works nights at a bar in Austin, Texas, to make ends meet while pursuing her dream of becoming a singer/songwriter. Luke is an army trainee, about to ship out for duty, who finds comfort in the unswerving discipline of service. But a chance encounter at Cassie's bar changes the course of both their lives.

What if the person you thought you knew best turns out to be someone you never knew at all? Andrea Cooper knows everything about her mother, Laura. She knows Laura has spent nearly her whole life in the small beach town of Belle Isle, Georgia; she knows Laura's never wanted anything more than to lead a quiet, normal life in this conventional community; she knows Laura's a kind and beloved speech pathologist who helps others; she knows Laura's never kept a secret in her life. Andrea knows that Laura is everything she isn't—confident, settled, sure of herself.

Misbah is a dreamer and storyteller, newly married to Toufiq in an arranged match. After their young life is shaken by tragedy, they come to the United States and open the Clouds' Rest Inn Motel, hoping for a new start.

Sadie hasn't had an easy life. Growing up on her own, she's been raising her sister, Mattie, in an isolated small town, trying her best to provide a normal life and keep their heads above water. But when Mattie is found dead, Sadie's entire world crumbles. After a somewhat botched police investigation, Sadie is determined to bring her sister's killer to justice and hits the road following a few meager clues to find him. When West McCray - a radio personality working on a segment about forgotten towns in America - overhears Sadie's story, he becomes obsessed with finding the girl.

Being the middle child has its ups and downs. But for Grace, an only child who was adopted at birth, discovering that she is a middle child is a different ride altogether. After putting her own baby up for adoption, she goes looking for her biological family, including: Maya, her loudmouthed younger bio sister, who has a lot to say about their newfound family ties. And Joaquin, their stoic older bio brother, who has no interest in bonding over their shared biological mother.

It's been several years since Carly Vega's parents were deported. Carly lives with her older brother, studies hard, and works the graveyard shift at a convenience store to earn enough to bring her parents back from Mexico.

It was a hot summer day when I met him on the construction site next to my parents' house. Under the sweat and dirt, Manning Sutter was as handsome as the sun was bright. He was older, darker, experienced. I wore a smiley-face t-shirt and had never even been kissed. I was too young, he said. I would wait. But I'd learn that no matter what you achieve in life, it means nothing if you suffer the heartbreak that comes with falling for someone you can never have. Because even though I saw Manning first, that didn't matter. My older sister saw him next.

After the sudden collapse of her family, Mim Malone is dragged from her home in Northern Ohio to the wastelands of Mississippi, where she lives in a medicated milieu with her dad and new stepmom. Before the dust has a chance to settle, she learns her mother is sick back in Cleveland. So she ditches her new life and hops aboard a northbound Greyhound bus to her real home and her real mother, meeting a quirky cast of fellow travelers along the way.

They call it The Violence: a strange epidemic that causes the infected to experience sudden bursts of animalistic rage, with no provocation and no memory of their crimes. While it tears the nation apart, one woman sees something unlikely in the chaos—an opportunity.

In the male-dominated field of animation, Mel Vaught and Sharon Kisses are a dynamic duo, the friction of their differences driving them: Sharon, quietly ambitious but self-doubting; Mel, brash and unapologetic, always the life of the party. Best friends and artistic partners since the first week of college, where they bonded over their working-class roots and obvious talent, they spent their twenties ensconced in a gritty Brooklyn studio. Working, drinking, laughing.

When Adam Blake lands the best elective ever in his senior year, serving as an aide to the school psychologist, he thinks he's got it made. Sure, it means a lot of sitting around, which isn't easy for a guy with ADHD, but he can't complain, since he gets to spend the period texting all his friends. Then the doctor asks him to track down the troubled freshman who keeps dodging her, and Adam discovers that the boy is Julian - the foster brother he hasn't seen in five years.

When Kevin finds Sarah stranded by the side of the road, he’s more than willing to give her a ride. Young, beautiful and distraught—she’s everything a single guy could ask for in a girl. What he doesn’t know is that she already has a guy: an abusive, drunken boyfriend who left her there in a fit of rage. And when that boyfriend comes back and finds Sarah missing, a simple ride will turn deadly.

Ramona was only five years old when Hurricane Katrina changed her life forever. Since then it's been Ramona and her family against the world. Standing over six feet tall, with unmistakable blue hair, Ramona is sure of three things: She likes girls, she's fiercely devoted to her family, and she knows she's destined for something bigger than the trailer she calls home in Eulogy, Mississippi. But juggling multiple jobs, her flaky mom, and her well-meaning but ineffectual dad forces her to be the adult of the family.

When Lise Redding's estranged sister, country-pop star Callie Redfern, is killed during a publicity stunt, the small-town music teacher is dragged from her quiet life into the spotlight. Lise hadn't spoken with Callie in ten years, ever since Callie's betrayal split them apart, so she's shocked to discover that she's inherited her sister's massive estate. Not only that, but Lise is now the guardian of her sixteen-year-old niece, Ariel, to whom she's practically a stranger.

Sixteen-year-old physics nerd Aysel is obsessed with plotting her own death. With a mother who can barely look at her without wincing, classmates who whisper behind her back, and a father whose violent crime rocked her small town, Aysel is ready to turn her potential energy into nothingness.