On the surface, these seven women are as different as can be - but each has had her share of bad luck, from cheating husbands to sexist colleagues to a legal system that often doesn't do its job. Now, drawn together by tragedy, they're forging a bond that will help them right the wrongs committed against them and discover an inner strength they didn't know they had. The Sisterhood is learning that when bad things happen, you can roll over and play dead...or you can get up fighting...

After years of trying to become pregnant without success, Rachel Dawson and her husband Thomas felt their dreams had finally come true the day they brought home their newly adopted twin babies. Though the lawyer Baron Bell who arranged for the surrogate mother charged a hefty six-figure fee, one glance into the eyes of their precious children told them it was all worth it - until the birth mother reappeared, first demanding more money, then the twins themselves.

Through public triumphs and private sorrows, the men in the Sisters' lives - husbands, friends, colleagues, and lovers - have offered invaluable aid and support. In the process, they've become an informal brotherhood of their own, able to relate to the unique challenges and rewards of life among the vigilantes.

Mateo Castillo is a rising star chef on the Manhattan culinary scene. But just as he’s about to reap the rewards of his skill and hard work by being featured on a major TV cooking competition, Mateo collapses in his restaurant’s kitchen—and regains consciousness in a hospital emergency room. If it weren’t for a security guard finding him in time, Mateo would have bled to death. The cause of his sudden illness is as mysterious as it is worrying, and Mateo and his family undergo a battery of genetic tests. Yet the answers that start to emerge only raise more questions.

Teresa "Toots" Amelia Loudenberry has crammed a great deal of living - not to mention eight much-loved husbands - into her varied and rewarding life. Newly single, Toots is ready to taste life again, and fate has just handed her the perfect opportunity.

College senior Lily Madison is on her own and desperate to pay for her last semester of school. With nowhere to turn, she makes the difficult decision to donate her eggs to a fertility clinic. Sam Parker is also a penniless student who supplements his tuition money by visiting a sperm bank. One day, Lily and Sam meet at the clinic and talk about their secret. Despite their obvious attraction, Lily and Sam go their separate ways.

When a brother-and-sister team uncover dangerous information hidden in an antique, they have no one to turn to but themselves in the first installment in a suspenseful new series by legendary, number one New York Times best-selling author Fern Michaels.

When Samantha Rainford - newly wed to Douglas Cosmo Rainford III - returns home from her honeymoon to find divorce papers waiting, she's shocked and heartbroken. Then she discovers that she's not the first to be abandoned - she's one of four (or maybe more) ex-Mrs. Rainfords - and decides it's time to put into practice that old truism: Don't get mad, get even.

Back in college, Jane Lewis would have given anything to be like homecoming queen Connie Bryan. Instead she was just Plain Jane - overweight, frumpy, and painfully shy. That was then. Today, a lovely and confident Dr. Jane Lewis has a thriving psychotherapy practice, her own radio talk show, a beautiful old Louisiana mansion, and her affectionate, nutty dog, Olive, to keep her company. The only thing missing is someone to share her life.

As far as former NFL star Jake Masters is concerned, dreams are risky propositions. Years ago he came achingly close to achieving his ambition of playing in the Super Bowl - before a spinal injury ended his career. Confined to a wheelchair, unwilling to take a chance on another risky surgery that could restore his mobility, Jake now stays cocooned behind the imposing gates of his lavish home.

For generations, the Windsors have lived on the family's grand estate in Crestwood, South Carolina, as intertwined with local life as sweet tea and pecan pie. Now, on the anniversary of her daughter Emily's death, Sarabess Windsor believes she may be the last to carry the family name - unless she can find her second daughter, Trinity, who disappeared 15 years ago.

An only child who lost both parents during her first year at college, wealthy heiress Kristine Kelly had made her husband her whole world. But she didn't see what everyone else did: that handsome, charismatic Logan Kelly was a manipulator and a user. Then, one cold December, Kristine got a chilling wake-up call when Logan vanished, along with the eight-million-dollar trust fund she had naively given him the power to control.

Gus Hollister owes all his success to his feisty grandmother, Rose, and he knows it. It was Rose and her two sisters, Iris and Violet, who raised Gus, sent him to the best schools, and helped him start his own accounting business. Rose even bought the house Gus lives in with his wife, Elaine. But now, Gus stands to lose everything - his home, his car, and his business. Worse, he’s alienated his beloved grandma, who tried to warn him about Elaine’s greedy, gold-digging ways.

Professional mountaineer Lily is building a new life for herself - in ways she never would have expected. She's traded the mountain wilderness of Wyoming for the lush river country of the deep South, where she is busy restoring a fine old Natchez, Mississippi house. And she's rediscovered happiness with Matt Starr, the man she has always loved. But Lily's dreams for the future are suddenly threatened when Matt disappears without a trace.

Ellie Bowman barely remembers the incident that put her into a coma. When she awoke, filled with unease, all she knew for certain was that her boyfriend, Rick, was missing. She knew she needed to get away from her old life and recover in safety. With the proceeds of a video game she helped develop, Ellie starts over in rural Missouri, working from her cottage and trusting no one except her friend and business partner.