Andrea Sachs, a small-town girl fresh out of college, is hired as the assistant to Miranda Priestly, the successful editor of Runway magazine. Andrea finds herself in an office that shouts Prada! Armani! Versace! at every turn. As things escalate from the merely unacceptable to the downright outrageous, Andrea begins to realize that the job a million girls would die for may just kill her. And even if she survives, she has to decide whether the job is worth the price of her soul.

When Imogen returns to work at Glossy after six months away, she can barely recognize her own magazine. Eve, fresh out of Harvard Business School, has fired "the gray hairs", put the managing editor in a supply closet, stopped using the landlines, and hired a bevy of manicured and questionably attired underlings who text and tweet their way through meetings.

As a publicist with a large, respected New York publishing house, Kate finds herself at the mercy of a broken publishing system, books that don’t sell, and author egos that are often, well, as big as the island of Manhattan. Enter the star editor, MacDermott Ellis: Tall, handsome, charismatic, married, and ready to save the day. Then there's Allan Lavigne, once a revered author - now as forgotten as last year's best sellers and his nephew Nick: Tall, gorgeous, sweet, single, and ready to sweep Kate off her feet.

Heartbroken, Veronica feels lost. Salvatore and Antoinette, her dead grandparents, begin to visit her dreams in an attempt to steer her in the right direction. At their suggestion, Veronica takes a news reporting class, which leads to a challenging freelance assignment covering a conspiracy trial. She also begins dating an unlikely suitor: creative Syd Blackman. Just when her love life and career are looking up, Veronica is tossed back to square one by an event that makes her question all her new choices.

He was tall, at least six feet, with dirty blond hair that hung over his eyes. His T-shirt read Nietzsche Is My Homeboy. So, that was Matt. Who Julie Seagles likes. A lot. But there is also Finn. Who she flat out loves. Complicated? Awkward? Completely. But really, how was this freshly-minted Boston transplant and newbie college freshman supposed to know that she would end up living with the family of an old friend of her mother’s? This was all supposed to be temporary.

Best friends, Casey and Rachel couldn't lead more different lives. While workaholic Casey rubs elbows with celebrities daily as the host of Gossip TV and comes home nightly to an empty apartment, stay-at-home mom Rachel juggles a baby, two teenagers, and a husband who barely seems the man she fell in love with two decades before. After an argument at their 20th high school reunion, Casey and Rachel throw back shots to get the night back on track. Instead, they get a life-changing hangover.

Marriage counselor Paige Reinhardt is counting down the days to summer, eager to reconnect with her workaholic husband at their cozy rental cottage in the Hamptons. But soon a mysterious crisis at Dave's work ruins their getaway plans. Paige is still figuring out how to handle the unexplained chill in her marriage when her troubled sister suddenly returns after a two-decade silence. Now, instead of enjoying the lazy summer days along the ocean, Paige is navigating the rocky waters of a forgotten bond with her sister in the sweltering city heat.

Ellen and Andy's first year of marriage doesn't just seem perfect, it is perfect. There is no question how deep their devotion is, and how naturally they bring out the best in each other. But one fateful afternoon, Ellen runs into Leo for the first time in eight years. Leo, the one who brought out the worst in her. Leo, the one who left her heartbroken with no explanation. Leo, the one she could never quite forget. When his reappearance ignites long-dormant emotions, Ellen begins to question whether the life she's living is the one she's meant to live.

Charlie Goldwyn's life hasn't exactly gone according to plan. A widower at 34, he is left trying to raise a quirky five-year-old, Caleb, whose obsession with natural disasters and penchant for girls' clothing have made him a loner at his preschool. The only thing Charlie does have going for him is his job at a prestigious law firm where - after 10 long years of 12-hour days and working through weekends and a huge win on a settlement - he is finally a rising star on his way to becoming a partner.

Cousins Mari, Erica, Selena, and Gracie are inseparable. They aren’t just family but best friends—sharing secrets, traditions, and a fierce love for their abuelita. But their idyllic childhood ends when Mari’s parents divorce, forcing her to move away. With Mari gone, the girls’ tight-knit bond unravels.

Sam is, to say the least, bookish. An English major of the highest order, her diet has always been Austen, Dickens, and Shakespeare. The problem is that both her prose and conversation tend to be more Elizabeth Bennet than Samantha Moore. But life for the 23-year-old orphan is about to get stranger than fiction. An anonymous, Dickensian benefactor calling himself Mr. Knightley offers to put Sam through Northwestern University’s prestigious Medill School of Journalism. There is only one catch: Sam must write frequent letters to the mysterious donor, detailing her progress.

Ambitious, confident, and successful, Joi-Marie believes she has it all figured out. At 28 years old, she has an enviable job as a producer, covering entertainment in New York City. Her close-knit family is loving and encouraging, and her boyfriend, Adam, is as close to perfect as you can get - except for the fact that he won't propose.

Lucy Silchester has received an appointment card. Actually, she's been invited along a few times to this appointment, but she keeps brushing the gold-embossed envelope under the shag pile carpet. She's taken her eye off the ball and has busied herself with work (a job she doesn't love), helping out friends, fixing her car, feeding her cat, seeing her family, and devoting her time to their life dramas. But Lucy is about to find out that this is one appointment that she can't miss.

Meryl Becker is living a mother's dream. Meg, the oldest of her three beautiful daughters, is engaged to a wonderful man from one of the country's most prominent families. Of course, Meryl wants to give Meg the perfect wedding - who wouldn't? But when her two younger daughters, Amy and Jo, also become engaged to celebrated bachelors, Meryl has to admit that three weddings is more than she and her husband, Hugh, can realistically afford. The solution? A triple wedding!

Leigh, Adriana and Emmy are best friends, all leading different lives and about to make some extreme choices. The three girls meet for dinner one evening and make a pact - they each have to change one thing in their lives by the end of the year.