
Neuroscientist Explains How To Rewire Your Depressed Brain | Manesh Girn
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About this listen
Can psychedelics really help heal depression, trauma, and addiction? Neuroscientist Dr. Manesh Girn joins us to break down exactly how substances like psilocybin, DMT, ketamine, and 5-MeO-DMT change your brain, and why they’re giving hope to millions who feel stuck in rigid, negative mind patterns.
In this deep yet easy-to-understand episode, we talk about:
Depression: Why your mind gets stuck, symptoms, and why low mood isn’t just “low serotonin.”
- Mind Flexibility: Why a healthy brain is flexible, not rigid, and how psychedelics open it up.
- Neuroplasticity: How your brain rewires itself, for better or worse.
- Ketamine & SSRIs: How they really work to lift you out of dark mental loops.
- Striatum & Addiction: Why old brain regions make habits so hard to break.
- Brain Networks: Neurons, default mode network, and the science of complex thoughts.
- Consciousness: Is it more than just the brain? Dr. Manesh shares his own beliefs.
- Inner Healing Intelligence: How psychedelics unlock your mind’s built-in wisdom to heal.
- Lifestyle & Integration: Why sleep, food, exercise, and intention matter more than you think.
- Future of Psychedelics: Challenges, research at UCSF, and how society can make this safe for all.
✨ Whether you’re curious about mental health, fascinated by neuroscience, or wondering if these substances can really transform lives, this is the clearest, most real conversation you’ll hear.
✅ About Dr. Manesh Girn
Dr. Manesh Girn is a neuroscientist at UCSF, a top researcher exploring psychedelics, the brain, and mental health. He’s published 20+ peer-reviewed studies, teaches thousands through The Psychedelic Scientist, and runs the Center for Minds, which studies how psychedelics, meditation, and creativity shape our lives.
👤 About Marpa Minds
Marpa Minds is a next-generation mental health network offering Spravato and Ketamine treatments for depression, trauma, and emotional numbness. We combine science, therapy, and compassion to help you feel again.
👉 Learn more about Marpa Minds: www.marpaminds.com
🔗 Follow Us:
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✅ 🔗 CONNECT
🎓 LinkedIn Dr. Girn: https://www.linkedin.com/in/manesh-girn
📚 Youtube: https://www.youtube.com/c/ThePsychedelicScientist
📸 Instagram: https://www.instagram.com/thepsychedelicscientist/?hl=en
If you found this valuable, hit LIKE & SUBSCRIBE, let’s break mental chains together. 💪🧠
#Neuroscience #MentalHealth #Psychedelics #MaraMinds