In Being Mortal, best-selling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending. Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit.

Two-thirds of us have experienced at least one adverse childhood experience, or ACE, such as abuse, neglect, parental substance dependence, or mental illness. Even though these events may have occurred long ago, they have the power to haunt us long into adulthood, and now we have found that they may even contribute to lifelong illness. Dr. Nadine Burke Harris, the founder/CEO of the Center for Youth Wellness and recipient of the Arnold P. Gold Foundation Humanism in Medicine Award, expands on similar topics as in her popular TED talk.

Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their 12 children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the 10 Galvin boys, one after another, were diagnosed as schizophrenic.

In this partially autobiographical work, best-selling author Lewis Thomas offers insights on subjects as wide-ranging as gender differences, how it feels to be a patient, human vs. computer intelligence, the future of cancer research, and the longevity of the planet—interspersing all with charming anecdotes about his family, his colleagues and himself.

As a health-care journalist, Kate Pickert knew the emotional highs and lows of medical treatment well - but always from a distance, through the stories of her subjects. That is, until she was unexpectedly diagnosed with an aggressive type of breast cancer at the age of 35. As she underwent more than a year of treatment, Pickert realized that the popular understanding of breast care in America bears little resemblance to the experiences of today's patients and the rapidly changing science designed to save their lives.

When former New York Times journalist Dan Koeppel texted his cousin Robert Meyer, a 20-year veteran of the emergency room at Montefiore Medical Center in the Bronx, at the beginning of the COVID-19 crisis in the United States, he expected to hear that things were hectic. On a scale of 1 to 10, 10 being overwhelmed, where do you think you are? Koeppel asked. Meyer’s grave reply - 100 - was merely the cusp of the crisis that would soon touch every part of the globe.

Over the next ten years, 40 to 60 million people in this country will be admitted to the ICU. Most of these hospitalizations will be sudden, unexpected, and harrowing experiences that can alter patients and their families physically and emotionally, with effects that endure for years. In this rich blend of science, medical history, profoundly humane patient stories, and personal reflection, Dr. Wes Ely describes his mission to prevent patients from being inadvertently harmed by the technology that is keeping them alive.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

For centuries, doctors have struggled to define mental illness - how do you diagnose it, how do you treat it, how do you even know what it is? In search of an answer, in the 1970s a Stanford psychologist named David Rosenhan and seven other people - sane, normal, well-adjusted members of society - went undercover into asylums around America to test the legitimacy of psychiatry's labels. Rosenhan's watershed study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever.

Leaving a life marked by crippling setbacks and his father's doubt, in 1967 a 20-something doctor from India arrived in America with only five dollars and the desire to claim his American dream. Faced with an entirely new culture, racism, and the lasting effects of disabling childhood injuries, through hard work and perseverance he overcame all odds. Now having performed over 15,000 open-heart surgeries, more than nearly every surgeon in history, Dr. Singh reflects on his most memorable patients and his incredible personal life.

In her early 20s, investigative journalist Anna Mehler Paperny had already landed her dream job. On the surface, her life was great. Nevertheless, she spiraled out, attempted suicide (the first of more attempts to follow), and landed in the ICU and then in a psych ward before setting out to tackle her recovery. In Hello I Want to Die Please Fix Me, Mehler Paperny turns her journalist's eye on her own experience and others' - in the ward; as an outpatient; facing family, friends, and coworkers; finding the right meds; trying to stay insured and employed.

Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work.

The technology invented by psychiatrist Robert G. Heath at Tulane University in 1950s and 60s has been described as one of "the most controversial yet largely undocumented experiments in US history" - controversial to us because Heath's patients included incarcerated convicts and gay men to be 'cured' of their sexual preference; controversial in its day because his work was allegedly part of MKUltra, the CIA's notorious "mind control" project. As a result, Heath's cutting-edge research and legacy were put under lock and key, buried in Tulane's archives.

Growing up in a New Jersey factory town in the 1980s, Daisy Hernández believed that her aunt had become deathly ill from eating an apple. No one in her family, in either the United States or Colombia, spoke of infectious diseases, and even into her 30s, she only knew that her aunt had died of a rare illness called Chagas. But as Hernández dug deeper, she discovered that Chagas - or the kissing bug disease - is more prevalent in the United States than the Zika virus.

Something was wrong with Peter. Eilene Zimmerman noticed that her ex-husband looked thin, seemed distracted, and was frequently absent from activities with their children. Yet in many ways, Peter seemed to have it all. So begins Smacked, a brilliant and moving memoir of Eilene’s shocking discovery, one that sets her on a journey to find out how a man she knew for nearly 30 years became a drug addict, hiding it so well that neither she nor anyone else in his life suspected what was happening.