After enduring a childhood of horrific abuse and crushing poverty, Tucker seeks refuge in her rural Tennessee home. The three grandchildren she is raising are her only connection to the outside, and her demeanor is purposefully rough. But her world is turned upside down when a new neighbor, Ella, moves into the old McDaniel place next door.

Mary Thomson is no ordinary woman. She works alongside her husband William cutting firewood to sell in the city, earning the nickname “The Woodcutter’s Wife”. The one thing she cannot seem to handle is the melancholy that has enveloped her...Her world flies apart when William disappears, leaving her with the arduous task of tending their farm by herself...she finds help in the form of a freed slave who offers his help. But fate throws her another dramatic curve, forcing her to make the most difficult choice of her life.

Symphony Nelson has weathered more than her share of hardships - in part thanks to the faithfulness and affection of her adopted puppy, Toby. Her formerly chaotic life seems to be settling down, until a peaceful walk in the woods leads Symphony and Toby to the reclusive cabin of Caleb Showalter, who knows more about her past than he's telling.

Roscoe Ransom returned home from World War I, broken both in body and spirit, drowning his pain daily in a bottle of whiskey. But even alcohol can’t numb the agony of losing his wife or the fear of trying to raise his son, Junior, alone. However, the mind-numbing predictability of Roscoe’s life as a sharecropper and his role of town sheriff - a job given to him out of pity when he returned from the war - is suddenly upended when a black man in their tiny community is murdered and castrated.

Early one morning in 1929, Mary Seneca Steele spontaneously packs a suitcase, gathers up her son and daughter, and drives away in her abusive and dissolute husband’s brand-new Auburn Phaeton automobile, leaving her privileged life in Charleston behind. It is the beginning of a journey of enlightenment that leads Mary “Sen” to the mountains and mysteries of Appalachia, where she will learn unexpected family secrets, create a new life for herself and her children, and finally experience love and happiness before tragedy will once again test her.

When 15-year-old Marigold becomes pregnant amid the Great Depression, she is rejected by her family and forced to fend for herself. And when she loses her baby in the forest, her whole world turns upside down. She’s even more distraught upon discovering she has an inexplicable power that makes her both beautiful and terrifying - and something of a local legend. Meanwhile, migrant workers Vern and Paul discover a violet-eyed baby and take it upon themselves to care for her.

Sugar arrives in the small town of Bigelow, Arkansas, like an ominous storm. She saunters down the street in a blonde wig and spiked heels, cigarette dangling between red-painted lips. Without even speaking to her, the women in town hate her. But when she moves in next door to Pearl, a woman who tragically lost her daughter 15 years earlier, the two women bond over tragic pasts.

In 1958 Georgia, the shade of a 13-year-old black girl's skin can make the difference in her fate. Tangy Mae is the smartest of her mother's 10 children, but she is also the darkest complected. The Quinns - all different skin shades, all with unknown fathers - live with their charismatic, beautiful, and tyrannical mother, Rozelle, in poverty on the fringes of a Georgia town where Jim Crow rules. Rozelle's children live in fear of her mood swings and her violence, but they are devoted to her. Rozelle pulls her children out of school when they are 12 years old so that they can help support her by going to work.

Anne Gallagher grew up enchanted by her grandfather’s stories of Ireland. Heartbroken at his death, she travels to his childhood home to spread his ashes. There, overcome with memories of the man she adored and consumed by a history she never knew, she is pulled into another time. The Ireland of 1921, teetering on the edge of war, is a dangerous place in which to awaken. But there Anne finds herself, hurt, disoriented, and under the care of Dr. Thomas Smith, guardian to a young boy who is oddly familiar.

When Kate Bowman temporarily moves to her grandmother’s Missouri farm with her husband and baby son, she learns that the lessons that most enrich our lives often come unexpectedly. The family has given Kate the job of convincing Grandma Rose, who's become increasingly stubborn and forgetful, to move off her beloved land and into a nursing home. But Kate knows such a change would break her grandmother’s heart.

In the ruggedness of the beautiful Kentucky mountains, Honey Lovett has always known that the old ways can make a hard life harder. As the daughter of the famed blue-skinned Troublesome Creek packhorse librarian, Honey and her family have been hiding from the law all her life. But when her mother and father are imprisoned, Honey realizes she must fight to stay free, or risk being sent away for good.

Del Wensley, wife of the most celebrated preacher in Harlan County, tries to mind her place. Until her husband’s infidelity pushes an already strained marriage to a breaking point. Clinging to her last hope for self-respect, Del turns her back on the rigid life she’s known. A coal train is rolling through the valley. With her eyes wide open to the unfamiliar, and to the freedom she craves, Del takes to the rails.

Mary Roberts is an impoverished child living in a council flat in 1950s London. When she and her sister are left at an orphanage by their mother, they don't think their lives can get any worse. Harry Evans is an orphan who finds himself, with Mary and her sister, on board a ship bound for Australia. They're sent to a farm school for children, where abuse and neglect are rife. A journey that will change their lives forever and from which they’ll never return.

At Cold Mountain Penitentiary, the convicted killers on E Block await their turn to walk the Green Mile and keep a date with the electric chair. Paul Edgecombe has seen his share of oddities in his years working as a guard on the Mile, but he's never met anyone like John Coffey.

Midwife Patience Murphy has a gift: a talent for escorting mothers through the challenges of bringing children into the world. Working in the hardscrabble conditions of Appalachia during the Depression, Patience takes the jobs that no one else wants, helping those most in need - and least likely to pay. She knows a successful midwifery practice must be built on a foundation of openness and trust - but the secrets Patience is keeping are far too intimate and fragile for her to ever let anyone in.