At 32 Russell Green has it all: a stunning wife, a lovable six-year-old daughter, a successful career as an advertising executive, and an expansive home in Charlotte. He is living the dream, and his marriage to the bewitching Vivian is the center of that. But underneath the shiny surface of this perfect existence, fault lines are beginning to appear, and no one is more surprised than Russ when he finds every aspect of the life he took for granted turned upside down.

In 1985, Yale Tishman, the development director for an art gallery in Chicago, is about to pull off an amazing coup, bringing in an extraordinary collection of 1920s paintings as a gift to the gallery. Yet as his career begins to flourish, the carnage of the AIDS epidemic grows around him. One by one, his friends are dying and after his friend Nico's funeral, the virus circles closer and closer to Yale himself. Soon the only person he has left is Fiona, Nico's little sister.

How can you be best friends with someone who keeps secrets from you - important secrets? Stephanie’s best friend is Rachel. Since second grade they’ve shared everything, good and bad. Now, as they start seventh grade, Stephanie meets Alison, who has just moved to their neighborhood. Stephanie hopes all three of them can be best friends, because she really likes Alison. But is it possible to have two best friends? Or is it true that two’s company, three’s a crowd?

In this moving story about losing and finding love again, a woman sets out to find the perfect matches for those closest to her. Forty-eight-year-old Nantucketer Dabney Kimball Beech has always had a gift for matchmaking. Some call her ability mystical, while others, her husband, celebrated economist John Boxmiller Beech, and her daughter, Agnes, who is clearly engaged to the wrong man, call it meddlesome. But there's no arguing with her results: With 42 happy couples to her credit and all of them still together, Dabney has never been wrong about romance.

Marnie MacGraw wants an ordinary life - a husband, kids, and a minivan in the suburbs. Now that she’s marrying the man of her dreams, she’s sure this is the life she’ll get. Then Marnie meets Blix Holliday, her fiancé’s irascible matchmaking great-aunt who’s dying, and everything changes - just as Blix told her it would. When her marriage ends after two miserable weeks, Marnie is understandably shocked.

When Lauren and Ryan’s marriage reaches the breaking point, they come up with an unconventional plan. They decide to take a year off in the hopes of finding a way to fall in love again. One year apart, and only one rule: they cannot contact each other. Aside from that, anything goes. Lauren embarks on a journey of self-discovery, quickly finding that her friends and family have their own ideas about the meaning of marriage. These influences, as well as her own healing process and the challenges of living apart from Ryan, begin to change Lauren’s ideas about monogamy and marriage.

Kelley Quinn is the owner of Nantucket's Winter Street Inn and the proud father of four, all of them grown and living in varying states of disarray. Patrick, the eldest, is a hedge fund manager with a guilty conscience. Kevin, a bartender, is secretly sleeping with a French housekeeper named Isabelle. Ava, a school teacher, is finally dating the perfect guy but can't get him to commit. And Bart, the youngest and only child of Kelley's second marriage to Mitzi, has recently shocked everyone by joining the Marines.

To be admired by someone we admire - we all yearn for this: the private, electrifying pleasure of being singled out by someone of esteem. But sometimes it can also mean entry to a new kind of life, a bigger world. Greer Kadetsky is a shy college freshman when she meets the woman she hopes will change her life. Faith Frank, dazzlingly persuasive and elegant at 63, has been a central pillar of the women’s movement for decades, a figure who inspires others to influence the world.

A warm June evening, a local tradition: The students of Nantucket High have gathered for a bonfire on the beach. But what begins as a graduation night celebration ends in tragedy after a horrible car crash leaves the driver of the car, Penny Alistair, dead and her twin brother in a coma. The other passengers - Penny's boyfriend Jake and her friend Demeter - are physically unhurt, but the emotional damage is overwhelming, and questions linger about what happened before Penny took the wheel.

Jill MacSweeny just wishes everything could go back to normal. But ever since her dad died, she's been isolating herself from her boyfriend, her best friends - everyone who wants to support her. And when her mom decides to adopt a baby, it feels like she's somehow trying to replace a lost family member with a new one.

Fifteen-year-old Rae Maddox’s mom, Gina, is a big fan of fresh starts. Gina thinks of them as an adventure, but for Rae, each move is just one more friend lost, one more chance to feel like an outsider. After arriving in Wisconsin, Gina promises to stay put until Rae graduates. Cautiously optimistic, she wades into the social whirl at Whitman High School, making a few friends and even earning a chance at love. But when the vice principal pairs her with fellow newbie Allison Daly, Rae’s tentative happiness is jeopardized.

Newly orphaned, recently divorced, and semiadrift, Nina Popkin is on a search for her birth mother. She's spent her life looking into strangers' faces, fantasizing they're related to her, and now, at thirty-five, she's ready for answers. Meanwhile, the last thing Lindy McIntyre wants is someone like Nina bursting into her life, announcing that they're sisters and campaigning to track down their mother. She's too busy with her successful salon, three children, beautiful home, and...oh yes, some pesky little anxiety attacks.

Marina Keegan's star was on the rise when she graduated magna cum laude from Yale in May 2012. She had a play that was to be produced at the New York International Fringe Festival and a job waiting for her at the New Yorker. Tragically, five days after graduation, Marina died in a car crash. Even though she was just 22 when she died, Marina left behind a rich, expansive trove of prose that, like her title essay, captures the hope, uncertainty, and possibility of her generation.

Judy Lohden is your above-average 16-year-old: sarcastic and vulnerable, talented and uncertain, full of big dreams for a big future. With a singing voice that can shake an auditorium, she should be the star of Darcy Arts Academy, the local performing-arts high school. So why is a girl this promising hiding out in a seedy motel room on the edge of town?

Beth and Jennifer know their company monitors their office email. But the women still spend all day sending each other messages, gossiping about their coworkers at the newspaper and baring their personal lives like an open book. Jennifer tells Beth everything she can't seem to tell her husband about her anxieties over starting a family. And Beth tells Jennifer everything, period. When Lincoln applied to be an internet security officer, he hardly imagined he'd be sifting through other people's inboxes like some sort of electronic Peeping Tom.